Evidence map›Paper›PMID 41241912›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2026

Proteomic Identification of Microproteins Translated from Long Non-coding RNA.

Jing Zhang, Zi-Hong Fan, Qing-Yu He, Yang Wang

Abstract read
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In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jing ZhangMOE Key Laboratory of Tumor Molecular Biology, College of Life Science and Technology, Jinan University, Guangzhou, China.
Zi-Hong FanMOE Key Laboratory of Tumor Molecular Biology, College of Life Science and Technology, Jinan University, Guangzhou, China.
Qing-Yu HeMOE Key Laboratory of Tumor Molecular Biology, College of Life Science and Technology, Jinan University, Guangzhou, China. tqyhe@email.jnu.edu.cn.
Yang WangMOE Key Laboratory of Tumor Molecular Biology, College of Life Science and Technology, Jinan University, Guangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The identification and exploration of microproteins encoded by long noncoding RNA (lncRNA) genes have the potential to revolutionize our understanding of human biology and expedite medical breakthroughs. Proteomics enables the identification and quantification of thousands of proteins present in cells, tissues or organisms, with LC-MS/MS serving as a pivotal technique in current proteomic research. Here, we describe a comprehensive suite of integrated methods to enhance proteomic analysis for the identification of lncRNA-encoded microproteins. This approach combines tricine gel electrophoresis, in-gel digestion, the establishment of a customized microprotein reference database, and LC-MS/MS analysis.

Indexed as

Protein BiosynthesisProteomicsRNA, Long NoncodingChromatography, LiquidDatabases, ProteinHumansMicropeptidesTandem Mass SpectrometryMicropeptidesRNA, Long NoncodingCustomized microprotein reference databaseIn-gel digestionLncRNAMicroproteinsProteomicsTricine gel electrophoresis

Identifiers

PMID41241912

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.