Evidence map›Paper›PMID 41241863›Full record

ArticleACS infectious diseases2025

Mechanistic Insights into the Role of Extracellular Vesicles at the Bacterial-Host Interface.

Miriana Battista, Christoph Saffer, Marc Thilo Figge, Cláudia Vilhena

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Miriana BattistaFriedrich-Alexander-Universität Erlangen-Nürnberg, Department Biology, Bacterial Interface Dynamics lab, Erlangen 91058, Germany.
Christoph SafferHKI-Center for Systems Biology of Infection, Leibniz-Institute for Natural Product Research and Infection Biology, Department of Applied Systems Biology, Jena 07745, Germany.
Marc Thilo FiggeHKI-Center for Systems Biology of Infection, Leibniz-Institute for Natural Product Research and Infection Biology, Department of Applied Systems Biology, Jena 07745, Germany.
Cláudia VilhenaFriedrich-Alexander-Universität Erlangen-Nürnberg, Department Biology, Bacterial Interface Dynamics lab, Erlangen 91058, Germany.ORCID 0000-0003-2884-8970

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacterial and human cells produce extracellular vesicles (EVs) in response to diverse stimuli, e.g., toxins, oxidative stress, nutrient depletion, or high cell density. Here, we describe a cocultivation platform that allows recovery of mixed extracellular vesicles (mix-EVs) produced simultaneously by both cell types. We investigated interactions between Gram-positive and Gram-negative bacteria (

Indexed as

Extracellular VesiclesGram-Negative BacteriaGram-Positive BacteriaHost-Pathogen InteractionsLeukocytes, MononuclearHumansInterleukin-1betaInterleukin-1 Receptor-Associated KinasesSignal TransductionStaphylococcus aureusTNF Receptor-Associated Factor 6Toll-Like Receptor 2Toll-Like Receptor 4IL1B protein, humanInterleukin-1betaInterleukin-1 Receptor-Associated KinasesIRAK1 protein, humanTLR2 protein, humanTLR4 protein, humanTNF Receptor-Associated Factor 6Toll-Like Receptor 2Toll-Like Receptor 4exosomesextracellular vesicleshost−pathogensignaling pathway

Identifiers

PMID41241863
PMCPMC12706781

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.