Trial reportHead & face medicine2025
The role of the hyoid bone in mandibular advancement: insights from functional appliance therapy in patients with skeletal class II - a prospective cohort study.
Trial report in Head & face medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Comparison of the Effects of Functional Treatment and Orthognathic Surgery on Hyoid Bone Position Following Mandibular Advancement.Turkish journal of orthodontics · 2026Article
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
STUDY
objectivesFunctional orthopedics induces mandibular advancement caused by neuromuscular adaptations. These adaptations can affect the position of the hyoid bone and may contribute to the amount of skeletal outcomes. The skeletal response is triggered by the quality and quantity of growth as well as muscular reactions. The aim of this clinical trial was to evaluate the hyoid bone position before and after functional orthodontic treatment.
methodsThis prospective cohort study included 31 patients (mean age: 12.3 ± 0.9 years) with skeletal class II meeting the following inclusion criteria: ANB > 4°, > ½ Class II molar relationship, overjet > 6 mm, neutral/horizontal growth pattern, and CVMS II-III. All patients were treated with the Sander Bite Jumping Appliance (BJA) with wear time monitored through microsensors. Lateral cephalograms were taken at baseline (t0) and after 1 year (t1). Linear and angular hyoid measurements were analyzed. Statistical analysis was performed using IBM SPSS (v29.0.2.0), employing paired t-tests and an exploratory post hoc grouping based on total mandibular length changes (Δco-pg), with significance set at p < 0.05.
resultsBJA therapy resulted in a significant more superior and anterior position of the hyoid in all patients. A greater increase in Δco-pg at t1 was associated with a more pronounced hyoid shift, while patients with a less Δco-pg showed a more inferior hyoid position at t0 and a greater tendency towards a vertical growth pattern.
conclusionA more inferior initial hyoid position was associated with limited mandibular advancement, suggesting a potential anatomical link to airway physiology, warranting further investigation into its implications for OSA risk. CLINICAL
trial registrationGerman Clinical Trials Register (DRKS); URL: http://www.germanctr.de; Identifier: DRKS00021090; registration date: 12.03.2020.
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