Evidence map›Paper›PMID 41241710›Full record

ArticleAnnals of surgical oncology2026

Postoperative Impact of Closed Incision Negative Pressure Therapy Following Oncoplastic Breast Surgery.

N Harris, P Aiello, D Detz, D Hanssen, C Farrell, C Balsay-Patel, J Whiting, S Hoover, N Khakpour, J Kiluk and 5 more

Abstract read
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In one paragraph

Article in Annals of surgical oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

N HarrisBreast Oncology, Moffitt Cancer Center, Tampa, Florida, USA. nbharris@mdanderson.org.
P AielloDepartment of Breast Oncology, H. Lee Moffitt Cancer Center and Research Center Inc, Tampa, Florida, USA.
D DetzDepartment of Breast Oncology, H. Lee Moffitt Cancer Center and Research Center Inc, Tampa, Florida, USA.
D HanssenUniversity of Texas McGovern Medical School, Houston, Texas, USA.
C FarrellUniversity of Texas McGovern Medical School, Houston, Texas, USA.
C Balsay-PatelDepartment of Cutaneous Oncology, Moffitt Cancer Center, Tampa, Florida, USA.
J WhitingH. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA.
S HooverBreast Oncology, Moffitt Cancer Center, Tampa, Florida, USA.
N KhakpourWomen's Oncology, Moffitt Cancer Center, Tampa, Florida, USA.
J KilukMoffitt Cancer Center Breast, Tampa, Florida, USA.
L KruperGeneral and Oncologic Surgery, Moffitt Cancer Center, Tampa, Florida, USA.
C LarongaMoffitt Cancer Center DIO, Tampa, Florida, USA.
M MalloryBreast Oncology, H. Lee Moffitt Cancer Center and Research Center Inc, Tampa, Florida, USA.
M C LeeComprehensive Breast Program, H. Lee Moffitt Cancer Center, Tampa, Florida, USA.
B CzernieckiBreast Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe application of closed incision negative pressure therapy (ciNPT) systems over closed surgical incisions purportedly lowers postoperative complications; however, there is little evidence to support its use in oncoplastic breast surgery. The primary objective of this study was to compare major and minor wound complication rates in patients with breast cancer undergoing oncoplastic procedures, with and without the use of the ciNPT. PATIENTS AND

methodsA prospectively maintained database of patients undergoing breast conserving oncoplastic procedures with placement of ciNPT system at a single institution was queried. This cohort was compared with a retrospective contemporaneous control group receiving primary two-layered suture and skin adhesive closure only. Major complications included abscess/hematoma/seroma needing drainage, and wound breakdown or asymmetry requiring return to the OR. Minor complications included breast lymphedema/erythema, minor nipple necrosis, and wound breakdown or mild asymmetry not requiring return to OR. Analyses were performed using Chi-square test or Fisher's exact test, where applicable, and univariate logistic regression models, with statistical significance set at p < 0.05.

resultsOf 186 patients, there were 93 in the ciNPT and 93 in the control group. There were significantly fewer major complications in the ciNPT group (1.1% ciNPT versus 10.8% control, p = 0.010). There was no significant difference in the rates of minor complications, and no difference in complication rates based on comorbidities or tumor characteristics.

conclusionsciNPT decreases major postoperative wound complications in patients with breast cancer undergoing oncoplastic procedures. Minimization of major postoperative complications can help ensure the timely initiation of adjuvant therapy following breast conserving oncoplastic procedures.

Indexed as

Breast NeoplasmsMammaplastyMastectomy, SegmentalNegative-Pressure Wound TherapyPostoperative ComplicationsAdultAgedCase-Control StudiesFemaleFollow-Up StudiesHumansMiddle AgedPrognosisProspective StudiesRetrospective StudiesBreast conserving surgeryClosed incision negative pressure therapyOncoplastic surgery

Identifiers

PMID41241710

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.