Evidence map›Paper›PMID 41241702›Full record

Trial reportJournal of anesthesia2026

Factors associated with changes in the quality of postoperative recovery after laparoscopic colorectal cancer surgery in women: a linear mixed-effects analysis.

Tongfeng Luo, Chunmeng Lin, Shan Li, Jiayi Zheng, Shimin Zhang, Yang Zhao

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Journal of anesthesia, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Tongfeng Luo *Department of Anesthesia, The Sixth Affiliated Hospital, Sun Yat-Sen University, No. 26 Yuancunerheng Road, Guangzhou, 510655, China.
Chunmeng Lin *Department of Anesthesia, The Sixth Affiliated Hospital, Sun Yat-Sen University, No. 26 Yuancunerheng Road, Guangzhou, 510655, China.
Shan Li *Department of Anesthesia, The Sixth Affiliated Hospital, Sun Yat-Sen University, No. 26 Yuancunerheng Road, Guangzhou, 510655, China.
Jiayi ZhengDepartment of Anesthesia, The Sixth Affiliated Hospital, Sun Yat-Sen University, No. 26 Yuancunerheng Road, Guangzhou, 510655, China.
Shimin ZhangDepartment of Anesthesia, The Sixth Affiliated Hospital, Sun Yat-Sen University, No. 26 Yuancunerheng Road, Guangzhou, 510655, China.
Yang ZhaoDepartment of Anesthesia, The Sixth Affiliated Hospital, Sun Yat-Sen University, No. 26 Yuancunerheng Road, Guangzhou, 510655, China. zhaoy47@mail.sysu.edu.cn.ORCID http://orcid.org/0000-0002-5603-9735

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeLaparoscopic surgery for colorectal cancer is performed globally. A 15-item quality of recovery (QoR-15) score is commonly used to evaluate postoperative recovery. However, women are particularly at risk for postoperative nausea and vomiting (PONV), anxiety and poorer overall recovery. Therefore, this study aims to evaluate the factors associated with changes in postoperative QoR-15 scores based on clinical features in women undergoing laparoscopic colorectal cancer surgery.

methodsWomen who underwent laparoscopic colorectal cancer surgery in a randomized controlled trial (FDP-PONV trial) were included in this secondary analysis. Clinical variables were collected during the perioperative period in the original FDP-PONV trial. The explanatory factors were entered into a multiple linear mixed model for further selection.

resultsOverall, 852 female patients were included in this study. A linear mixed model was constructed over time with two clinically relevant factors. QoR-15 scores improved over time. Neoadjuvant chemotherapy was positively associated with changes in postoperative QoR-15 scores. Intraoperative hypertension was negatively associated with changes in postoperative QoR-15 scores.

conclusionNeoadjuvant chemotherapy and intraoperative hypertension were associated with changes in the quality of recovery following laparoscopic colorectal cancer surgery in women.

Indexed as

Colorectal NeoplasmsLaparoscopyAgedColorectal Surgical ProceduresFemaleHumansHypertensionLinear ModelsMiddle AgedNeoadjuvant TherapyPostoperative Nausea and VomitingColorectal cancerLaparoscopic surgeryQuality of recoveryWomen

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.