Trial reportJournal of anesthesia2026
Factors associated with changes in the quality of postoperative recovery after laparoscopic colorectal cancer surgery in women: a linear mixed-effects analysis.
Trial report in Journal of anesthesia, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Authors and funding
6 authors.
Funding
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Abstract
purposeLaparoscopic surgery for colorectal cancer is performed globally. A 15-item quality of recovery (QoR-15) score is commonly used to evaluate postoperative recovery. However, women are particularly at risk for postoperative nausea and vomiting (PONV), anxiety and poorer overall recovery. Therefore, this study aims to evaluate the factors associated with changes in postoperative QoR-15 scores based on clinical features in women undergoing laparoscopic colorectal cancer surgery.
methodsWomen who underwent laparoscopic colorectal cancer surgery in a randomized controlled trial (FDP-PONV trial) were included in this secondary analysis. Clinical variables were collected during the perioperative period in the original FDP-PONV trial. The explanatory factors were entered into a multiple linear mixed model for further selection.
resultsOverall, 852 female patients were included in this study. A linear mixed model was constructed over time with two clinically relevant factors. QoR-15 scores improved over time. Neoadjuvant chemotherapy was positively associated with changes in postoperative QoR-15 scores. Intraoperative hypertension was negatively associated with changes in postoperative QoR-15 scores.
conclusionNeoadjuvant chemotherapy and intraoperative hypertension were associated with changes in the quality of recovery following laparoscopic colorectal cancer surgery in women.
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