Evidence map›Paper›PMID 41241694›Full record

ArticleMetabolomics : Official journal of the Metabolomic Society2025

PMI estimation through

Alberto Chighine, Matteo Stocchero, Fabio De-Giorgio, Riccardo Fratini, Giorgia Fanunza, Radhika Kesharwani, Camilla Gozzelino, Matteo Nioi, Ernesto d'Aloja, Emanuela Locci

Abstract readValidation Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Metabolomics : Official journal of the Metabolomic Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Alberto ChighineDepartment of Medical Sciences and Public Health, Section of Legal Medicine, University of Cagliari, Cagliari, CA, Italy.ORCID http://orcid.org/0000-0003-0952-9712
Matteo StoccheroDepartment of Women's and Children's Health, University of Padova, Padova, Italy.ORCID http://orcid.org/0000-0001-9296-8390
Fabio De-GiorgioDepartment of Health Surveillance and Bioethics, Section of Legal Medicine, Catholic University of Rome, Rome, Italy.ORCID http://orcid.org/0000-0001-7433-0924
Riccardo FratiniDepartment of Medical Sciences and Public Health, Section of Legal Medicine, University of Cagliari, Cagliari, CA, Italy.ORCID https://orcid.org/0009-0006-6354-9000
Giorgia FanunzaDepartment of Medical Sciences and Public Health, Section of Legal Medicine, University of Cagliari, Cagliari, CA, Italy.ORCID https://orcid.org/0009-0002-5798-3848
Radhika KesharwaniDepartment of Medical Sciences and Public Health, Section of Legal Medicine, University of Cagliari, Cagliari, CA, Italy.ORCID https://orcid.org/0000-0003-4924-4519
Camilla GozzelinoDepartment of Medical Sciences and Public Health, Section of Legal Medicine, University of Cagliari, Cagliari, CA, Italy.ORCID https://orcid.org/0009-0000-7160-0984
Matteo NioiDepartment of Medical Sciences and Public Health, Section of Legal Medicine, University of Cagliari, Cagliari, CA, Italy.ORCID https://orcid.org/0000-0002-3645-6005
Ernesto d'AlojaDepartment of Medical Sciences and Public Health, Section of Legal Medicine, University of Cagliari, Cagliari, CA, Italy.ORCID http://orcid.org/0000-0003-4456-6252
Emanuela LocciDepartment of Medical Sciences and Public Health, Section of Legal Medicine, University of Cagliari, Cagliari, CA, Italy. elocci@unica.it.ORCID http://orcid.org/0000-0003-0237-4228

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study builds on a prior proof-of-concept metabolomic analysis of post-mortem pericardial fluid to assess its reproducibility and validate its utility for estimating the post-mortem interval. Sixty-five pericardial fluid samples were collected during medico-legal autopsies in two different Forensic Medicine Institutes with post-mortem intervals spanning 16 to 199 h. Samples underwent liquid-liquid extraction and

Indexed as

MetabolomicsPericardial FluidPostmortem ChangesProton Magnetic Resonance SpectroscopyAdultAgedAged, 80 and overAutopsyFemaleHumansMaleMiddle AgedReproducibility of Results1H NMR metabolomicsExtraction protocolHuman pericardial fluidPMIPost-mortemTime since death

Identifiers

PMID41241694
PMCPMC12619721

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.