Evidence map›Paper›PMID 41241386›Full record

SynthesisThe Angle orthodontist2026

Effectiveness of deciduous molar anchorage for rapid maxillary expansion: a systematic review and meta-analysis.

Marco Serafin, Massimiliano Vella, Elisa Boccalari, Alberto Caprioglio

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in The Angle orthodontist, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Marco Serafin
Massimiliano Vella
Elisa Boccalari
Alberto Caprioglio

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: To evaluate dentoskeletal effectiveness of deciduous molar anchorage in rapid maxillary expansion (RME) during mixed dentition. Materials and Methods: A comprehensive search was conducted across PubMed, MEDLINE, Scopus, and Cochrane Library databases from January 2000 to March 2025, adhering to PRISMA guidelines. Included studies comprised randomized controlled trials (RCTs) and non-RCTs assessing RME anchored to deciduous molars in patients with mixed dentition. Risk of bias (ROB) was assessed using ROB2 for RCTs and ROBINS-I for non-RCTs. Data were synthesized using a random-effects meta-analysis, focusing on dental and skeletal expansion. Results: Seventeen studies (six RCTs, 11 retrospective) met the inclusion criteria. A meta-analysis of 12 studies demonstrated significant transverse changes in all evaluated areas: deciduous canines (4.27 mm), deciduous molars (5.51 mm), permanent molars (3.93 mm), and skeletal expansion (2.59 mm). Notably, dental expansion significantly exceeded skeletal expansion. Subgroup analyses comparing Haas and Hyrax expanders revealed no statistically significant differences in dentoskeletal expansion outcomes. However, heterogeneity across studies ranged from moderate to high. ROB assessments indicated moderate risk in all RCTs, whereas non-RCTs ranged from low to serious risk. Funnel plot inspection revealed no substantial asymmetry, suggesting a low likelihood of publication bias. Conclusions: This meta-analysis confirms that deciduous molar anchorage in RME significantly increases dentoskeletal transverse dimensions. No significant differences emerged between appliance designs (Haas vs Hyrax). Despite consistent expansion effectiveness, variability in study design and ROB must be considered when interpreting these results.

Indexed as

MolarOrthodontic Anchorage ProceduresPalatal Expansion TechniqueTooth, DeciduousChildDentition, MixedHumansAnchorageDeciduous teethMeta-analysisRapid maxillary expansionSystematic review

Identifiers

PMID41241386
PMCPMC12962274

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.