Evidence map›Paper›PMID 41241077›Full record

ArticleJournal of affective disorders2026

When breath lifts your mood: Dynamic everyday links between breathing, affect, and emotion regulation in remitted depression.

Sean A Minns, Bruna Martins-Klein, Sarah L Zapetis, Ellie P Xu, Jiani Li, Gabriel A León, Margarid R Turnamian, Desiree Webb, Archita Tharanipathy, Emily Givens and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of affective disorders, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. The impact of emotion regulation strategies on experiential and physiological responses to negative emotional videos.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Sean A MinnsDepartment of Psychology, University of Southern California, Los Angeles, CA, USA.
Bruna Martins-KleinDepartment of Psychology, University of Southern California, Los Angeles, CA, USA.
Sarah L ZapetisDepartment of Psychology, University of Southern California, Los Angeles, CA, USA.
Ellie P XuDepartment of Psychology, University of Southern California, Los Angeles, CA, USA.
Jiani LiDepartment of Psychology, University of Southern California, Los Angeles, CA, USA.
Gabriel A LeónDepartment of Psychology, University of Southern California, Los Angeles, CA, USA.
Margarid R TurnamianDepartment of Psychology, University of Southern California, Los Angeles, CA, USA.
Desiree WebbDepartment of Psychology, University of Southern California, Los Angeles, CA, USA.
Archita TharanipathyDepartment of Psychology, University of Southern California, Los Angeles, CA, USA.
Emily GivensDepartment of Psychology, University of Southern California, Los Angeles, CA, USA.
Jonathan P StangeDepartment of Psychology, University of Southern California, Los Angeles, CA, USA; Department of Psychiatry and Behavioral Sciences, University of Southern California, Los Angeles, CA, USA. Electronic address: jstange@usc.edu.

Funding

Southern California Clinical and Translational Science InstituteUL1TR001855 · NCATS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Thomas A Buchanan, Michele D. Kipke · 2016 to 2026
$81.3M
Southern California Clinical and Translational Science InstituteUL1TR000130 · NCATS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI BUCHANAN, THOMAS A · 2012 to 2015
$36.0M
Strengthening Stakeholder Engagement in Human Research Protections.UL1TR002003 · NCATS · UNIVERSITY OF ILLINOIS AT CHICAGO · PI KARNIK, NIRANJAN SUBHASH, MERMELSTEIN, ROBIN J. · 2016 to 2024
$33.7M
Ambulatory phenotyping with real-time indices of discordant affect regulation: Exploring opportunities for targeted intervention in depressionR01MH133842 · NIMH · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Jonathan P Stange · 2023 to 2026
$3.0M
From Networks to the Real World: Integrating Neural and Autonomic Processes of LossK23MH112769 · NIMH · UNIVERSITY OF SOUTHERN CALIFORNIA · PI STANGE, JONATHAN P · 2017 to 2021
$931k
Neural Mechanisms of Emotion Regulation Flexibility and Success in Everyday Life in DepressionF31MH136739 · NIMH · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Ellie Pin Xu · 2024 to 2026
$92k
NCATS NIH HHS UL1 TR000130NCATS NIH HHS UL1 TR001855NCATS NIH HHS UL1 TR002003NIMH NIH HHS F31 MH136739NIMH NIH HHS K23 MH112769NIMH NIH HHS R01 MH133842
6 · The paper itself

Abstract

backgroundInternalizing disorders are marked by emotional dysregulation and attenuated positive affect and emotion regulation deficits. Respiration increasingly has been recognized as a unique physiological marker that reflects and shapes emotional processes. Elucidating whether the link between respiration and positive affect is strengthened or weakened in those with remitted depression (rMDD) could have important treatment implications. Likewise, understanding the role of emotion regulation strategies in respiration-affect dynamics could inform targeted interventions.

methodsSeventy-three adults (36 rMDD, 37 healthy controls) completed a 7-day ambulatory protocol that included repeated ecological momentary assessments (EMAs) of affect, emotion regulation, and continuous respiratory monitoring via Hexoskin shirts. Respiratory metrics (mean tidal volume, breathing rate, and minute ventilation) were derived from the 30-min periods preceding each EMA. Multilevel models were used to examine within-person associations between respiration and subsequent affect, and to test moderation by diagnostic group and emotion regulation strategy.

resultsWithin-person increases in mean minute ventilation and breathing rate predicted subsequent increases in high-arousal positive affect (HAPA). The strength of the relationship between respiration and affect was moderated by history of depression as well as by average emotion regulation use. At the between-person level, individuals with more variable tidal volume demonstrated greater use of acceptance.

conclusionsThese findings suggest that respiratory patterns may influence dynamic affective functioning. Our results may offer important implications for developing treatment interventions, including just-in-time or novel breathing interventions to increase HAPA and potentially prevent relapse for individuals with rMDD.

Indexed as

AffectEmotional RegulationMajor Depressive DisorderRespirationAdultArousalEcological Momentary AssessmentFemaleHumansMaleMiddle AgedRespiratory RateYoung AdultAmbulatory monitoringDepressionEcological assessmentEmotion regulationPhysiologyPositive affectRespiration

Identifiers

PMID41241077
PMCPMC12682619

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.