ArticleMagnetic resonance in medicine2026
Free-Breathing Multi-Slice Co-Registered Cardiac T1, T2, and ADC Mapping With Spin-Echo Echo Planar Imaging.
Article in Magnetic resonance in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Free-Breathing Multi-Slice Co-Registered Cardiac T1, T2, and ADC Mapping With Spin-Echo Echo Planar Imaging.Magnetic resonance in medicine · 2026Article
- Diffusion Tensor MRI of the Heart: The Toolbox Continues to Grow.Circulation. Cardiovascular imaging · 2026Article
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Authors and funding
17 authors.
Funding
Abstract
purposeTo develop a free-breathing method for multi-slice co-registered cardiac T1, T2, and ADC maps using single-shot spin-echo echo planar imaging (SE-EPI).
methodsT1, T2, and diffusion weighted images in five slices were acquired with SE-EPI readouts during free breathing using interleaved acquisition of slices, non-selective inversion recovery, varying echo times (TE), and second-order motion-compensated diffusion gradients in three orthogonal directions with different b values. All images were registered to a single target image followed by parameter fitting to generate co-registered T1/T2/ADC maps. This approach was evaluated in phantom measurements, 13 healthy volunteers, two myocardial infarction (MI) swine, and two cardiac amyloidosis (CA) patients by comparison to reference mapping techniques. Qualitative assessments were performed by two expert readers.
resultsPhantom experiments showed strong agreement with reference measurements (R
conclusionsThe proposed method enables five-slice, co-registered, and free-breathing myocardial T1, T2, and ADC maps in less than 5 min, facilitating integrated multi-contrast tissue characterization in cardiac MRI. Future work will aim to optimize map quality and expand clinical applications.
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