ArticleChemistry & biodiversity2026
Comparative LC-MS Analysis and In Vitro Evaluation of Antioxidant, Antimicrobial, and Enzyme Inhibitory Properties of Ultrasound-Assisted and Soxhlet Extracts of Cachrys cristata DC.
Article in Chemistry & biodiversity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
This study evaluated the extraction efficiency, phenolic composition, and bioactivity of Cachrys cristata using different methods. Ultrasound-assisted extraction (US) yielded higher extract amounts and phenolic contents, including flavonoids and flavonols, compared to Soxhlet extraction (S). While US 70% ethanol gave the highest extract yield, the US methanol (MeOH) extract contained the highest total phenolic content (105.47 mg gallic acid equivalents/g dry extract) and was selected for LC-MS profiling. Seventeen compounds were identified, with gentisic acid (39.03/50.73 mg/L), ferulic acid (27.00/25.68 mg/L), and rutin (13.28/11.91 mg/L) as dominant in Soxhlet and US extracts, respectively. The US MeOH extract showed strong antioxidant activity in DPPH and ABTS assays and eightfold higher anti-tyrosinase activity than kojic acid, while no acetylcholinesterase inhibition was observed. The hexane extract exhibited potent antibacterial effects against Staphylococcus aureus, Enterococcus faecalis, and Listeria monocytogenes, inhibited biofilm formation and pyocyanin in Pseudomonas aeruginosa, and had limited antifungal activity. It also strongly inhibited bovine serum albumin denaturation (88.88% vs. 95.60% for diclofenac). For antidiabetic potential, the US methylene chloride extract inhibited α-amylase better than acarbose (IC
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.