Evidence map›Paper›PMID 41240205›Full record

ArticleNeurosurgical review2025

Hemodynamic differences between intracranial and extracranial dissecting aneurysms: An analysis of shear forces and their clinical implications.

Felipe Ramirez-Velandia, Vincenzo T R Loly, Emmanuel O Mensah, Vitor Lauar Pimenta de Figueiredo, Jean Filo, Rafael T Tatit, Mark Rotondo, João de Sá Brasil Lima, Carlos E Baccin, Christopher S Ogilvy

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In one paragraph

Article in Neurosurgical review, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Felipe Ramirez-VelandiaNeurosurgical Service, Harvard Medical School, Beth Israel Deaconess Medical Center, 110 Francis Street, Boston, MA, 02215, USA.
Vincenzo T R LolyHospital Israelita Albert Einstein, São Paulo, Brazil.
Emmanuel O MensahNeurosurgical Service, Harvard Medical School, Beth Israel Deaconess Medical Center, 110 Francis Street, Boston, MA, 02215, USA.
Vitor Lauar Pimenta de FigueiredoNeurosurgical Service, Harvard Medical School, Beth Israel Deaconess Medical Center, 110 Francis Street, Boston, MA, 02215, USA.
Jean FiloNeurosurgical Service, Harvard Medical School, Beth Israel Deaconess Medical Center, 110 Francis Street, Boston, MA, 02215, USA.
Rafael T TatitHospital Israelita Albert Einstein, São Paulo, Brazil.
Mark RotondoNeurosurgical Service, Harvard Medical School, Beth Israel Deaconess Medical Center, 110 Francis Street, Boston, MA, 02215, USA.
João de Sá Brasil LimaInstituto Mauá de Tecnologia, São Paulo, Brazil.
Carlos E BaccinHospital Israelita Albert Einstein, São Paulo, Brazil.
Christopher S OgilvyNeurosurgical Service, Harvard Medical School, Beth Israel Deaconess Medical Center, 110 Francis Street, Boston, MA, 02215, USA. cogilvy@bidmc.harvard.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intracranial carotid dissecting aneurysms (DA) are often treated emergently upon diagnosis. In contrast, extracranial DA are generally considered less likely to rupture and are commonly managed conservatively. Despite these clinical differences, limited data exists on the hemodynamic differences that might explain their divergent clinical behaviors. Retrospective analysis of intracranial and extracranial DA treated between 2011 to 2023. DA were reconstructed from computerized angiographic images using 3D Slicer software. Computational fluid dynamics (CFD) simulations were performed using ANSYS® Fluent package. Hemodynamic parameters calculated included time averaged wall shear stress (TAWSS), high shear areas (HSA), low shear areas (LSA), time averaged wall shear stress ratio (TAWSR), oscillatory shear index (OSI), and relative residence time (RRT). We compared these variables between extracranial and intracranial lesions using Mann-Whitney U and t-tests. Nineteen DA (10 extracranial, 9 intracranial) from 16 patients (age 48-82; 9 male) were analyzed. The average volume and area of the lesions evaluated were 187 mm

Indexed as

Aortic DissectionHemodynamicsIntracranial AneurysmAgedAged, 80 and overCerebral AngiographyFemaleHumansMaleMiddle AgedRetrospective StudiesSubarachnoid HemorrhageComputational Flow DynamicsDissecting AneurysmEndovascular TreatmentExtracranialIntracranialWall Shear Stress

Identifiers

PMID41240205

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.