Evidence map›Paper›PMID 41240180›Full record

ArticleNeurosurgical review2025

Efficacy of a synthetic collagen-based sealant (TachoSil

Pedro David Delgado-López, Ane Barreras-García, Ana Sabel Herrero Gutiérrez, Antonio Montalvo-Afonso, Rubén Diana Martín, Javier Martín-Alonso, Vicente Martín-Velasco

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neurosurgical review, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. TachoSilNeurosurgical review · 2026
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Pedro David Delgado-LópezNeurosurgery Department, Hospital Universitario de Burgos, Avda Islas Baleares 3, Burgos, 09006, Spain. pedrodl@yahoo.com.ORCID http://orcid.org/0000-0002-9317-6958
Ane Barreras-GarcíaNeurosurgery Department, Hospital Universitario de Burgos, Avda Islas Baleares 3, Burgos, 09006, Spain.
Ana Sabel Herrero GutiérrezNeurosurgery Nurse Department, Hospital Universitario de Burgos, Avda Islas Baleares 3, Burgos, 09006, Spain.
Antonio Montalvo-AfonsoNeurosurgery Department, Hospital Universitario de Burgos, Avda Islas Baleares 3, Burgos, 09006, Spain.ORCID http://orcid.org/0000-0003-2440-3237
Rubén Diana MartínNeurosurgery Department, Hospital Universitario de Burgos, Avda Islas Baleares 3, Burgos, 09006, Spain.
Javier Martín-AlonsoNeurosurgery Department, Hospital Universitario de Burgos, Avda Islas Baleares 3, Burgos, 09006, Spain.
Vicente Martín-VelascoNeurosurgery Department, Hospital Universitario de Burgos, Avda Islas Baleares 3, Burgos, 09006, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cerebrospinal fluid (CSF) leakage is a significant complication following planned or incidental durotomies during spinal surgery. While primary suturing remains the gold standard for dural closure, it is common to necessitate adjunctive reinforcement techniques. This study aims to evaluate the efficacy of a synthetic collagen-based sealant patch (TachoSil

Indexed as

Cerebrospinal Fluid LeakCollagenDura MaterFibrinogenNeurosurgical ProceduresPostoperative ComplicationsSpineThrombinAdultAgedAged, 80 and overCohort StudiesDrug CombinationsFemaleHumansMaleCollagenDrug CombinationsFibrinogenTachoSilThrombinCerebrospinal fluid leakCollagen-based sealantDural repairIncidental durotomySpinal surgeryTachoSil

Identifiers

PMID41240180
PMCPMC12619807

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.