Evidence map›Paper›PMID 41240122›Full record

ArticleArchives of virology2025

Hepatitis E virus subtype 3f infections: rare but increasingly identified in Japan.

Tatsunori Nakano, Hiroshi Okano, Satoko Uraki, Takahiro Ono, Atsuya Shimizu, Masaharu Takahashi, Shigeo Nagashima, Kazumoto Murata, Hiroaki Okamoto

Abstract read
PubMed Publisher
In one paragraph

Article in Archives of virology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Tatsunori NakanoDepartment of Internal Medicine, Fujita Health University Nanakuri Memorial Hospital, Tsu, Mie, 514-1295, Japan. tatsunakano@gmail.com.ORCID http://orcid.org/0000-0003-2682-3809
Hiroshi OkanoDepartment of Gastroenterology, Suzuka General Hospital, Suzuka, Mie, 513-0818, Japan.ORCID http://orcid.org/0000-0003-3612-7364
Satoko UrakiDepartment of Internal Medicine, Murase Hospital, Suzuka, Mie, 513-0801, Japan.
Takahiro OnoDepartment of Internal Medicine, Saiseikai Matsusaka General Hospital, Matsusaka, Mie, 515-0003, Japan.
Atsuya ShimizuDepartment of Internal Medicine, Saiseikai Matsusaka General Hospital, Matsusaka, Mie, 515-0003, Japan.
Masaharu TakahashiDivision of Virology, Department of Infection and Immunity, Jichi Medical University School of Medicine, Shimotsuke, Tochigi, 329-0498, Japan.ORCID http://orcid.org/0000-0001-6888-9318
Shigeo NagashimaDivision of Virology, Department of Infection and Immunity, Jichi Medical University School of Medicine, Shimotsuke, Tochigi, 329-0498, Japan.ORCID http://orcid.org/0000-0001-8944-713X
Kazumoto MurataDivision of Virology, Department of Infection and Immunity, Jichi Medical University School of Medicine, Shimotsuke, Tochigi, 329-0498, Japan.ORCID http://orcid.org/0000-0002-3419-6297
Hiroaki OkamotoDivision of Virology, Department of Infection and Immunity, Jichi Medical University School of Medicine, Shimotsuke, Tochigi, 329-0498, Japan.ORCID http://orcid.org/0000-0003-0827-0964

Funding

AMED JP25fk0210132
6 · The paper itself

Abstract

Forty-two human-derived hepatitis E virus subtype 3f (HEV-3f) strains, identified in Japan between 1998 and 2024, were analyzed based on their genome sequences. Fourteen strains in the Kanto region and two in Mie Prefecture exhibited close genetic relatedness to each other but were distinct from European HEV-3f strains, suggesting possible endemic circulation in Japan. Conversely, seven strains from individuals without a history of travel shared identical nucleotide sequences with European HEV-3f, suggesting that these infections were potentially linked to imported pork. Comprehensive molecular and epidemiological studies are needed to clarify the relative contributions of local zoonotic transmission from domestic or wild animals versus foodborne introduction via imported pork products.

Indexed as

Hepatitis EHepatitis E virusAdultAnimalsFemaleGenome, ViralGenotypeHumansJapanMaleMiddle AgedPhylogenyRNA, ViralSwineZoonosesRNA, Viral

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.