Evidence map›Paper›PMID 41240114›Full record

Trial reportWorld journal of urology2025

Enhanced recovery after surgery protocol does not reduce the length of postoperative hospitalization after robot-assisted radical prostatectomy. Outcomes from the first randomized controlled trial: the (PROSTA-RAAC) study.

G Pierquet, E Prévost, L Lopez, R Gaston, J Rouffilange, J Riviere, J B Roche, N Vuong, A Genty, J L Hoepffner and 2 more

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in World journal of urology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05172986 (Enhanced Recovery Program After a Robotic-assisted Surgery), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05172986 nacompletednot on this map

Enhanced Recovery Program After a Robotic-assisted Surgery (RAAC) of Radical Prostatectomy. PROSTA-RAAC

TypeinterventionalSponsorElsanRan2021 to 2023Enrolled135ConditionsProstate Cancer, Quality of Life, Recovery ProgrammArmsFollow-up patient program
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

G PierquetClinique Saint Augustin, ELSAN, 114 Avenue d'Arès, 33074, Bordeaux Cedex, France.
E PrévostClinique Saint Augustin, ELSAN, 114 Avenue d'Arès, 33074, Bordeaux Cedex, France.
L LopezClinique Saint Augustin, ELSAN, 114 Avenue d'Arès, 33074, Bordeaux Cedex, France.
R GastonClinique Saint Augustin, ELSAN, 114 Avenue d'Arès, 33074, Bordeaux Cedex, France.
J RouffilangeClinique Saint Augustin, ELSAN, 114 Avenue d'Arès, 33074, Bordeaux Cedex, France.
J RiviereClinique Saint Augustin, ELSAN, 114 Avenue d'Arès, 33074, Bordeaux Cedex, France.
J B RocheClinique Saint Augustin, ELSAN, 114 Avenue d'Arès, 33074, Bordeaux Cedex, France.
N VuongClinique Saint Augustin, ELSAN, 114 Avenue d'Arès, 33074, Bordeaux Cedex, France.
A GentyClinique Saint Augustin, ELSAN, 114 Avenue d'Arès, 33074, Bordeaux Cedex, France.
J L HoepffnerClinique Saint Augustin, ELSAN, 114 Avenue d'Arès, 33074, Bordeaux Cedex, France.
A D AsimakopoulosUnit of Urology, Fondazione PTV Policlinico Tor Vergata, Rome, Italy.
P T PiechaudClinique Saint Augustin, ELSAN, 114 Avenue d'Arès, 33074, Bordeaux Cedex, France. pthpiechaud@hotmail.fr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo provide the first randomized study assessing the impact of an Enhanced Recovery after Surgery (ERAS) program on the outcomes of robot-assisted radical prostatectomy (RARP).

methods129 consecutive patients affected by prostate cancer were randomly assigned to standard-of-care (SoC, 61 patients) or ERAS perioperative protocol (68 patients) during hospitalization for RARP. The differences between the SoC and the ERAS groups were based on preoperative fasting, premedication, anesthesia, analgesia, hydration, and nutrition. The primary endpoint of the study was to compare the length of postoperative hospitalization after RARP surgery between the two groups. Secondary endpoints were the time to autonomous mobilization, the rate of postoperative comorbidities, and patients' quality of life (QoL) as assessed by a validated questionnaire. The trial was registered on 21/12/2021 on ClinicalTrials.gov (NCT05172986).

resultsTime to autonomous mobilization after surgery was significantly shorter in the ERAS group than in the SoC group (11.9 ± 5.7 h for ERAS and 17.2 ± 5.0 h for SoC, p < 0.001). However, there was no statistically significant difference in the length of postoperative hospitalization (43.1 ± 10.4 vs. 43.7 ± 18.1 h for the SoC and ERAS group, respectively, p = 0.81), time to oral nutrition, complication rate within 30 days from surgery, and QoL domains.

conclusionPrehabilitation, surgical expertise, and optimized SoC may limit further benefits from ERAS in contemporary RARP. When these three conditions were satisfied, ERAS did not further reduce the length of postoperative hospitalization, time to oral nutrition, postoperative complications, and the impact of surgery on the main domains of the patient's QoL.

Indexed as

Enhanced Recovery After SurgeryLength of StayProstatectomyProstatic NeoplasmsRobotic Surgical ProceduresAgedHumansMaleMiddle AgedQuality of LifeTreatment OutcomeEnhanced recovery after surgeryHospitalization durationPatient outcomesProstate cancerProstatectomyRobotic prostatectomy

Identifiers

PMID41240114

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.