Evidence map›Paper›PMID 41240090›Full record

ArticlePediatric surgery international2025

Surgical resection of giant hepatoblastoma involving second and third hepatic portals: a study of 59 cases.

Chen Zhen, Qiao Guoliang, Ge Juntao, Chen Xinghai, Li Long

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Article in Pediatric surgery international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1 · What the graph read from it

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Chen Zhen *Department of General Surgery, Capital Center for Children's Health, Capital Medical University, Capital Institute of Pediatrics, Yabao Road2#, Chaoyang, Beijing, 100021, People's Republic of China.
Qiao Guoliang *Department of General Surgery, Capital Center for Children's Health, Capital Medical University, Capital Institute of Pediatrics, Yabao Road2#, Chaoyang, Beijing, 100021, People's Republic of China.
Ge Juntao *Department of Pediatric Surgery, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Jinan, 250014, Shandong province, People's Republic of China.
Chen XinghaiDepartment of General Surgery, Capital Center for Children's Health, Capital Medical University, Capital Institute of Pediatrics, Yabao Road2#, Chaoyang, Beijing, 100021, People's Republic of China. chenxinghai676767@163.com.
Li LongDepartment of General Surgery, Capital Center for Children's Health, Capital Medical University, Capital Institute of Pediatrics, Yabao Road2#, Chaoyang, Beijing, 100021, People's Republic of China. lilong676767@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA considerable proportion of pediatric giant hepatoblastoma cases involve the second and third hepatic portals (GHSTP), which were previously considered unresectable. Surgical management of such GHSTP-involved cases is associated with significant technical challenges. This retrospective study was designed to assess the feasibility and surgical approaches for pediatric giant hepatoblastoma with involvement of the second and third hepatic portals.

methodsFrom January 2006 to December 2024, 59 pediatric patients with giant hepatoblastoma involving the second and third hepatic portals (GHSTP) underwent partial hepatectomy. The therapeutic outcomes of these cases were retrospectively analyzed.

resultsAll 59 patients underwent successful liver tumor resection. The operative duration ranged from 160 to 350 min, with a mean of 270 min. First hepatic portal clamping was performed in all cases. The resection approaches were as follows: 13 cases underwent resection of segments V-VIII; 12 cases, resection of segments IV-VIII; 6 cases, resection of segments I-IV; 10 cases, resection of segments I, IV, and VIII; 8 cases, resection of segments I, IV, V, and VIII; 4 cases, resection of segment I plus segments V-VIII; and 6 cases, resection of segment I plus segments IV-VIII. There was no mortality, and postoperative complications occurred in 8 cases.

conclusionResection of giant hepatoblastoma involving the second and third hepatic portals remains technically challenging; however, with meticulous and accurate preoperative assessment coupled with a thorough understanding of hepatic anatomy, such tumor resection is feasible and can be performed with acceptable safety. Moreover, complete resection of this subset of tumors may effectively improve the long-term survival outcomes of patients with hepatoblastoma.

Indexed as

HepatectomyHepatoblastomaLiver NeoplasmsPortal VeinChildChild, PreschoolFeasibility StudiesFemaleHumansInfantMaleRetrospective StudiesTreatment OutcomeHepatic hilumHuge hepatic hepatoblastomSurgical resection

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