Evidence map›Paper›PMID 41239513›Full record

ArticlePerioperative medicine (London, England)2025

Analgesic effects of bilateral ultrasound-guided erector spinae plane block versus patient controlled intravenous analgesia in correction surgery for idiopathic scoliosis: study protocol for a randomized controlled trial.

Chenxi Liao, Jie Zhong, Xingning Lai, Ren Liao

Registry-linked trialAbstract read
In one paragraph

Article in Perioperative medicine (London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06728046 (Analgesic Effects of Ultrasound-Guided Erector Spinae Plane Block v.s Patient Controlled Analgesia in Correction Surgery for Idiopathic Scoliosis), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06728046 nanot yet recruitingnot on this map

Analgesic Effects of Ultrasound-Guided Erector Spinae Plane Block v.s Patient Controlled Analgesia in Correction Surgery for Idiopathic Scoliosis: A Randomized Controlled Trial

TypeinterventionalSponsorWest China HospitalRan2025 to 2027Enrolled40ConditionsIdiopathic Scoliosis, Erector Spinae Plane Block, Patient Controlled AnalgesiaArmsESPB, PCA
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Chenxi LiaoDepartment of Anesthesia and Operation Center, Research Unit for Perioperative Stress Assessment and Clinical Decision, Chinese Academy of Medical Sciences (2018RU012), West China Hospital of Sichuan University, No.37 Guo Xue Lane, Chengdu, Sichuan, 610041, China.ORCID http://orcid.org/0009-0008-1865-1932
Jie ZhongDepartment of Anesthesia and Operation Center, Research Unit for Perioperative Stress Assessment and Clinical Decision, Chinese Academy of Medical Sciences (2018RU012), West China Hospital of Sichuan University, No.37 Guo Xue Lane, Chengdu, Sichuan, 610041, China.ORCID http://orcid.org/0009-0003-3735-0282
Xingning LaiDepartment of Anesthesia and Operation Center, Research Unit for Perioperative Stress Assessment and Clinical Decision, Chinese Academy of Medical Sciences (2018RU012), West China Hospital of Sichuan University, No.37 Guo Xue Lane, Chengdu, Sichuan, 610041, China.ORCID http://orcid.org/0000-0001-9096-7474
Ren LiaoDepartment of Anesthesia and Operation Center, Research Unit for Perioperative Stress Assessment and Clinical Decision, Chinese Academy of Medical Sciences (2018RU012), West China Hospital of Sichuan University, No.37 Guo Xue Lane, Chengdu, Sichuan, 610041, China. liaoren7733@wchscu.cn.ORCID http://orcid.org/0000-0003-3963-4310

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundScoliosis correction surgery involves surgical wounds, intense intraoperative stimulation, and severe postoperative pain, often necessitating the use of potent-opioids-based patient-controlled intravenous analgesia (PCIA), which have obvious side effects. An effective pain management strategy with both ensuring sufficient analgesia and minimizing opioid-related adverse effects is an urgent need in clinical practice. The ultrasound-guided erector spinae plane block (ESPB) has been reported to provide effective and safe analgesia in many surgical types. Building on this evidence, we hypothesize that ESPB can significantly reduce postoperative pain scores, decrease perioperative opioid consumption, and mitigate opioid-related side effects when compared to PCIA.

methodsThis study is a randomized controlled trial designed to test the superiority of ESPB in providing postoperative analgesia compared with PCIA. Forty participants undergoing idiopathic scoliosis surgery will be enrolled and randomly allocated in a 1:1 ratio into either the ESPB group or the PCIA group. The primary outcome is the resting numerical rating scale (NRS) pain score within 2 h postoperatively. The secondary outcomes include perioperative opioid consumption, the incidence of opioid-related adverse effects, and postoperative NRS pain scores on movement. DISCUSSION: The study will provide evidence for ESPB as an innovative and effective method for postoperative analgesia in scoliosis correction surgery. The results of this trial will contribute to the development of multimodal analgesia regime for managing spinal surgery.

trial registrationThe National Institutes of Health Clinical Trials Registry, NCT06728046. Registered on December 6, 2024.

Indexed as

Erector spinae plane blockIdiopathic scoliosis correction surgeryPatient-controlled intravenous analgesiaRandomized controlled trial

Identifiers

PMID41239513
PMCPMC12619480

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.