Evidence map›Paper›PMID 41239437›Full record

ArticleInternational journal for equity in health2025

Socioeconomic gradients and mechanisms of chronic disease health literacy: the mediating role of preventive healthcare utilization in rural Shangdong, China.

Liansen Wang, Xinyu Xu, Rui Li, Yuxuan Zhang, Yingjie Cai, Jing Tang, Xiaowei Yang, Jing Han, Fangyao Chen, Xiuli Qiao

Abstract read
In one paragraph

Article in International journal for equity in health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Liansen Wang *Shandong Provincial Center for Disease Control and Prevention, Ji'nan, Shandong, 250014, China.
Xinyu Xu *Global Health Institute, Health Science Center, Xi'an Jiaotong University, Xi'an, Shaanxi, 712000, China.
Rui Li *Shandong Provincial Center for Disease Control and Prevention, Ji'nan, Shandong, 250014, China.
Yuxuan ZhangGlobal Health Institute, Health Science Center, Xi'an Jiaotong University, Xi'an, Shaanxi, 712000, China.
Yingjie CaiGlobal Health Institute, Health Science Center, Xi'an Jiaotong University, Xi'an, Shaanxi, 712000, China.
Jing TangGlobal Health Institute, Health Science Center, Xi'an Jiaotong University, Xi'an, Shaanxi, 712000, China.
Xiaowei YangGlobal Health Institute, Health Science Center, Xi'an Jiaotong University, Xi'an, Shaanxi, 712000, China.
Jing HanGlobal Health Institute, Health Science Center, Xi'an Jiaotong University, Xi'an, Shaanxi, 712000, China. bbbishop@126.com.ORCID 0000-0003-1460-0114
Fangyao ChenKey Laboratory for Disease Prevention and Control and Health Promotion of Shaanxi Province, Xi'an Jiaotong University, Xi'an, Shaanxi, 710061, China. chenfy@xjtu.edu.cn.
Xiuli QiaoMedical Records Management Department, Shandong Public Health Clinical Center, Ji'nan, Shandong, 250001, China. tthaoxinqing08@126.com.

Funding

Shandong Province Humanities and Social Sciences Research Projects 2023-JKZX-11Shandong Province Medical and Health Science and Technology Development Plan Project 202312071011
6 · The paper itself

Abstract

purposeTo explore the social determinants and underlying mechanisms of health literacy in managing chronic diseases, and to analyze how socioeconomic status (SES) influences it.

methodThis study, based on Shandong Province’s 2022 Health Literacy Surveillance Database, selected 2,826 residents from some, counties in Shandong eligible areas using multistage stratified cluster random sampling. It explored the social determinants of chronic disease health literacy using multiple linear regression, multiple logistic regression, interactive analysis and mediation analysis.

resultsHigher SES (High vs. Low: OR = 2.21, 95%CI: 1.68–2.91, P < 0.001; Medium vs. Low: OR = 1.36, 95%CI: 1.08–1.71, P = 0.009), elevated household income (Highest vs. Lowest category: OR = 2.58, 95%CI: 1.58–4.22, P < 0.001), and higher educational attainment (Bachelor’s vs. Primary: OR = 3.46, 95%CI: 2.06–5.81, P < 0.001) were positively associated with higher chronic disease literacy. However, patients specifically diagnosed with hypertension (OR = 2.27, 95%CI: 1.35–3.79), coronary heart disease (OR = 2.57, 95%CI: 1.14–5.81), or diabetes (OR = 2.37, 95%CI: 1.21–4.63) demonstrated significantly higher literacy levels. The preventive healthcare services (indirect effect = 0.017, 95% CI: 0.016–0.041, P < 0.001), changes in health behavior (indirect effect = 0.007, 95% CI: 0.002–0.020, P < 0.001), and frequency of physical examinations (indirect effect = 0.006, 95% CI: 0.004–0.015, P < 0.001) significantly mediated the relationship between SES and chronic disease literacy. Subgroup analysis showed that in the low SES group, women (OR = 0.60, 95% CI: 0.50–0.75, P < 0.001) and elders (OR = 0.70, 95% CI: 0.42–0.91, P = 0.001) had significantly lower chronic disease literacy than men and young participants.

conclusionThis study elucidates the multidimensional mechanisms by which SES impacts chronic disease health literacy and provides a scientific basis for developing targeted interventions.

Indexed as

Health LiteracyPatient Acceptance of Health CarePreventive Health ServicesRural PopulationSocial ClassAdultAgedChinaChronic DiseaseFemaleHumansMaleMiddle AgedSocioeconomic Disparities in HealthSocioeconomic FactorsAging populationChronic disease health literacyGender disparitiesHealth behavior changeHealth disparitiesLow-SES populationsMediation analysisPreventive healthcare utilizationRural ChinaSocioeconomic status (SES)

Identifiers

PMID41239437
PMCPMC12619406

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.