Observational studyHealth and quality of life outcomes2025
Quality of life in older adults (aged 60-80 years) after lung cancer surgery: a longitudinal observational study.
Observational study in Health and quality of life outcomes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Survival impact of pN2a and pN2b nodal status in stage IIB-IIIB non-small cell lung cancer under the 9Turk gogus kalp damar cerrahisi dergisi · 2026Article
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveAccurate health-related quality of life (HRQOL) data after video-assisted thoracic surgery (VATS) are lacking for older patients with non-small cell lung cancer (NSCLC). We aimed to characterize the trajectories of symptom burden and functional interference and identify predictors of delayed recovery.
methodsIn this longitudinal study, older adults (aged 60–80 years) with NSCLC undergoing VATS were enrolled. The MD Anderson Symptom Inventory for Lung Cancer (MDASI-LC) was used to assess symptom burden and functional interference at preoperative, discharge, and 7 days, 1, 2, 3, and 6 months after discharge.
resultsComplete prospective data were available for 250 of 254 consecutive patients (98.4% completion rate). The cohort had a median age of 68 years (IQR: 64–71) and comprised 40.9% men. The four most prevalent symptom items were fatigue, pain, shortness of breath, and coughing, while the four most prevalent interference items were general activity, work (including housework), walking, and enjoyment of life. By 6 months after discharge, 68.8% of patients overall returned to preoperative levels (symptoms: 66.9–83.5%; interference: 62.6–66.5%). Multivariable analysis identified the extent of VATS resection (wedge → segmentectomy → lobectomy)as an independent predictor of delayed recovery (ORs per increment:1.868–2.109, 95% CIs:1.260–3.157).
conclusionThe majority of older adults’ symptom burden and functional interference returned to preoperative levels 6 months after discharge. The extent of VATS resection was independently associated with delayed recovery. These findings advocate for the preoperative integration of recovery patterns into surgical strategy selection, particularly when weighing oncological radicality against geriatric patients’ physiological reserves.
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