Evidence map›Paper›PMID 41239401›Full record

ArticleJournal of neuroinflammation2025

A [

Leonie Jt Balter, Jonatan Malmros, Per Stenkrona, Andrea Varrone, Anton Forsberg, Erik Gustavsson, Cedrique E Mouyobo, Grégoria Kalpouzos, Goran Papenberg

Abstract read
In one paragraph

Article in Journal of neuroinflammation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Leonie Jt BalterDepartment of Clinical Neuroscience, Karolinska Institutet, Stockholm, 171 65, Sweden. leonie.balter@ki.se.
Jonatan MalmrosDepartment of Medical Sciences, Clinical Psychiatry, Uppsala University, Uppsala, 751 85, Sweden.
Per StenkronaDepartment of Clinical Neuroscience, Centre for Psychiatry Research, Region Stockholm, Karolinska Institutet, & Stockholm Health Care Services, Stockholm, 171 77, Sweden.
Andrea VarroneDepartment of Clinical Neuroscience, Centre for Psychiatry Research, Region Stockholm, Karolinska Institutet, & Stockholm Health Care Services, Stockholm, 171 77, Sweden.
Anton ForsbergDepartment of Clinical Neuroscience, Centre for Psychiatry Research, Region Stockholm, Karolinska Institutet, & Stockholm Health Care Services, Stockholm, 171 77, Sweden.
Erik GustavssonDepartment of Clinical Neuroscience, Karolinska Institutet, Stockholm, 171 65, Sweden.
Cedrique E MouyoboDepartment of Clinical Neuroscience, Centre for Psychiatry Research, Region Stockholm, Karolinska Institutet, & Stockholm Health Care Services, Stockholm, 171 77, Sweden.
Grégoria KalpouzosAging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, 171 77, Sweden.
Goran PapenbergAging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, 171 77, Sweden. goran.papenberg@ki.se.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sleep disturbances and inflammation are interconnected through shared regulatory mechanisms and are both implicated in age-related diseases. However, their connection at the level of brain-specific inflammation remains underexamined in humans. This study investigated whether specific dimensions of sleep are associated with microglial density, as measured by translocator protein (TSPO) levels, a biomarker of neuroinflammation. TSPO levels were measured using a single [

Indexed as

BrainMicrogliaPositron-Emission TomographySleepAcetamidesAgedAged, 80 and overCarbon RadioisotopesFemaleHumansMaleMiddle AgedReceptors, GABAAcetamidesCarbon RadioisotopesReceptors, GABATSPO protein, humanInflammationMicroglial densityNeuroinflammationPETSleep durationSleep healthTSPO

Identifiers

PMID41239401
PMCPMC12619189

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.