ArticleWorld journal of surgical oncology2025
Is conformal thyroidectomy feasible? A 5-10-year follow-up study of residual thyroid in 2512 cases after thyroidectomy.
Article in World journal of surgical oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
backgroundPapillary thyroid carcinoma (PTC) is the most common thyroid malignancy, and the balance between surgical extent (particularly non-total thyroidectomy [non-TX]) and postoperative recurrence risk in the residual thyroid remains a key clinical concern. This single-center retrospective study analyzed 2512 patients with unilateral PTC who underwent non-TTx between January 2014 and December 2024 and completed 5-10 years of follow-up evaluations, aiming to determine the recurrence rate in residual thyroid and related risk factors.
methodsThe Kaplan-Meier method was used to calculate cumulative recurrence-free survival (RT-RFS) in the residual thyroid. Independent risk factors were identified through univariate χ² tests and multivariate logistic regression analysis. The effect size for between-group differences in continuous variables was calculated using Cohen's d.
resultsThe overall recurrence rate was 5.8% with 5- and 10-y RT-RFS rates of 95.4% and 94.2%, respectively. Univariate analysis demonstrated significant associations between recurrence and age > 55 y, increased tumor size (T1a-T3), multifocality, preoperative subclinical hypothyroidism, and postoperative TSH > 2.0 mIU/L (all P < 0.05). Multivariate regression analysis confirmed tumor size (T1b/T2/T3 vs. T1a: OR = 2.253/5.053/19.452), multifocality (OR = 1.908), and postoperative TSH > 2.0 mIU/L (OR = 2.193) as independent risk factors for residual thyroid recurrence (all P < 0.05). However, neither the surgical extent of non-TTx, nor age, gender, preoperative subclinical hypothyroidism, and coexisting Hashimoto's thyroiditis are independent driving factors, and confirmed that there is no significant association between residual thyroid volume and postoperative recurrence risk.
conclusionFor patients with unilateral, unifocal PTC classified as T1a, we propose that conformal thyroidectomy represents a clinically appropriate and feasible alternative to unilateral thyroid lobectomy.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.