Evidence map›Paper›PMID 41239396›Full record

ArticleBMC psychology2025

The relationship between stress, anxiety and depression with sexual function among women with premature ovarian insufficiency in the West of Iran.

Ensiyeh Jenabi, Salman Khazaei, Azita Tiznobaik, Sara Abdoli, Sanaz Javadiyeganeh, Ali Ghaleiha, Shamim Pilehvari

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Article in BMC psychology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Ensiyeh JenabiMother and Child Care Research Center, Institute of Health Sciences and Technologies, Hamadan University of Medical Sciences, Hamadan, Iran.
Salman KhazaeiDepartment of Epidemiology, Research Center for Health Sciences, Hamadan University of Medical Sciences, Hamadan, Iran.
Azita TiznobaikMother and Child Care Research Center, Institute of Health Sciences and Technologies, Hamadan University of Medical Sciences, Hamadan, Iran.
Sara AbdoliStudent Research Committee, Hamadan University of Medical Sciences, Hamadan, Iran. sara.abdoli.m96@gmail.com.
Sanaz JavadiyeganehStudent Research Committee, Hamadan University of Medical Sciences, Hamadan, Iran.
Ali GhaleihaBehavioral Disorders and Substance Abuse Research Center, Hamadan University of Medical Sciences, Hamadan, Iran.
Shamim PilehvariFertility and Infertility Research Center, Hamadan University of Medical Sciences, Hamadan, Iran.

Funding

Hamadan University of Medical Sciences 140207045603
6 · The paper itself

Abstract

introductionGiven the prevalence of Primary ovarian insufficiency (POI) in the community and the limited number of studies on the impact of psychological factors on the sexual health of affected women, this study aimed to investigate the relationship between stress, anxiety and depression with sexual function among women with POI in the west of Iran.

methodsThis cross-sectional study was conducted on 240 women between December 2023 and April 2025. Participants included women with POI undergoing infertility treatment at the Fatemieh Infertility Center, a referral hospital in Hamadan, Iran. Data collection tools included a demographic and laboratory information form, the short form of the Depression, Anxiety, and Stress Scale (DASS-21), and the Female Sexual Function Index (FSFI) questionnaire. Statistical analyses were performed using Stata software (version 14; StataCorp LLC, College Station, TX, USA), with a significance level of 0.05 set for all p-values.

resultsDepression, anxiety, and stress exhibit strong inter-correlations (0.48-0.57) and robust inverse correlations with all sexual function domains (negative correlations up to -0.65). Components of the FSFI questionnaire (e.g., desire, arousal, satisfaction) demonstrate high correlations (0.57-0.85). In addition, among the categorical variables analyzed, only economic status (mean FSFI score: 14.55 for low-incomevs. 15.87 for middle-income, p = 0.02) and family history of infertility (mean FSFI: 14.24 with history vs. 15.86 without, p = 0.009) show statistically significant associations with total sexual function. The analysis of total mental health scores across categorical variables revealed that family history of infertility showed a statistically significant association (p = 0.009), with individuals reporting a family history scoring higher (Mean = 47.94, SD = 5.68) compared to those without (Mean = 45.15, SD = 6.87).

conclusionDepression, anxiety, and stress robust inverse correlations with all sexual function domains.Economic status and family history of infertility show statistically significant associations with total sexual function.Family history of infertility showed a statistically significant association with total mental health scores.Finding is recommended that psychological counseling classes be offered to women with POI.

Indexed as

AnxietyDepressionPrimary Ovarian InsufficiencySexual BehaviorSexual Dysfunctions, PsychologicalStress, PsychologicalAdultCross-Sectional StudiesFemaleHumansIranSurveys and QuestionnairesYoung AdultAnxietyDepressionOvarian insufficiencyStress

Identifiers

PMID41239396
PMCPMC12619433

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.