ArticleJournal of neuroengineering and rehabilitation2025
Neuromuscular adaptations in soleus and tibialis anterior muscles in persons with spinal cord injury.
Article in Journal of neuroengineering and rehabilitation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSpinal cord injury (SCI) can lead to various neurophysiological changes, altering the neural motor control strategies. The lower limb muscles are of high importance for locomotion; however, there exists a significant knowledge gap in neurophysiological changes following SCI in these muscles. This study aims to explore the neuromuscular adaptations in the soleus and tibialis anterior muscles in persons with incomplete SCI.
methodsAnkle joint torque, high-density electromyography (HD-EMG) and motor unit parameters of tibialis anterior and soleus were analyzed during repeated sub-maximal voluntary isometric contractions (20% and 50% of the maximal torque) and compared to those from a control cohort.
resultsWe observed muscle-dependent alterations in motor control between the SCI and control groups. Namely, SCI group required significantly higher normalized EMG amplitudes than the control group to achieve the same contraction levels. At 50% contraction level, compared to control group, the SCI group motor units were recruited at lower thresholds in both muscles and fired at lower rates in the tibialis anterior muscle. We observed no significant differences in intramuscular motor unit coherence or muscle co-contraction between the two groups.
conclusionsThe observed combination of between-group differences in motor unit behavior may indicate that even in muscles of high-functioning individuals with incomplete SCI, is a shift towards larger motor units in both tibialis anterior and soleus muscles. These results contribute to knowledge of neurophysiological modifications in major ankle muscles following a SCI and provide deeper insights into neurophysiological changes that can be used complementary to clinical SCI evaluation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.