Evidence map›Paper›PMID 41239316›Full record

ArticleBMC pediatrics2025

Prediction of complications from pediatric multiple magnet ingestion: development and validation of radiologic and clinical-radiologic nomograms in a large retrospective study.

Xiaohui Lai, Yizhen Luo, Songyu Teng, Yijiang Zhuang, Chenrui Zheng, Jianli Zhou, Xiongjian Cui, Qiru Su, Zhiyong Li, Hongwu Zeng

Abstract readValidation Study
In one paragraph

Article in BMC pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Xiaohui Lai *Department of Radiology, Third Affiliated Hospital of Shenzhen University (Luohu District People's Hospital), Shenzhen, 518000, China.
Yizhen Luo *Department of Radiology, Shenzhen Children's Hospital, Shenzhen, 518038, China.
Songyu TengDepartment of Radiology, Shenzhen Children's Hospital, Shenzhen, 518038, China.
Yijiang ZhuangDepartment of Radiology, Shenzhen Children's Hospital, Shenzhen, 518038, China.
Chenrui ZhengDepartment of Radiology, Shenzhen Children's Hospital, Shenzhen, 518038, China.
Jianli ZhouShantou University Medical College, Shantou University, Shantou, 515041, China.
Xiongjian CuiShantou University Medical College, Shantou University, Shantou, 515041, China.
Qiru SuShantou University Medical College, Shantou University, Shantou, 515041, China.
Zhiyong LiDepartment of Radiology, Shenzhen Children's Hospital, Shenzhen, 518038, China. li_33@126.com.
Hongwu ZengDepartment of Radiology, Shenzhen Children's Hospital, Shenzhen, 518038, China. homerzeng@126.com.

Funding

the Guangdong High-level Hospital Construction Fund ynkt2021-zz47the Sanming Project of Medicine in Shenzhen SZSM202011005the Shenzhen Science and Technology Plan Project No. JCYJ20230807093815031
6 · The paper itself

Abstract

backgroundCurrent clinical models for pediatric multiple magnet ingestion lack accuracy in asymptomatic patients and in cases with unreliable histories, while radiologic predictors remain unvalidated. This study aimed to develop and validate two nomograms integrating radiologic (± clinical) features for individualized risk stratification.

methodThis retrospective study analyzed data from 146 pediatric patients treated at Shenzhen Children's Hospital between 2017 and 2023. Risk factors were identified using the least absolute shrinkage and selection operator (LASSO) and multivariable logistic regression. Model performance was assessed using multiple metrics, with internal validation using 1000 bootstrap resamples.

resultsComplications occurred in 57 patients (39.0%; 65.1% male; median age, 4.6 years). Nomogram R (area under the receiver operating characteristic curve [AUC]: 0.85, 95% confidence interval [CI] 0.79-0.92; internally validated AUC: 0.86) included magnets size > 25 mm, blurred magnet edges, gap between magnets, and lack of progression on serial radiographs. Nomogram C&R (AUC: 0.95, 0.92-0.99; internally validated AUC: 0.96) incorporated multiple ingestions, vomiting, abdominal pain, magnets size > 25 mm, and lack of progression on serial radiographs. Both models demonstrated good fit (Hosmer-Lemeshow test), good calibration in calibration plots, and high clinical utility. Nomogram C&R demonstrated superior net reclassification improvement and integrated discrimination improvement. Sensitivity, specificity, and accuracy were 82.5%, 70.8%, and 75.3% for Nomogram R, and 87.7%, 92.1%, and 90.4% for Nomogram C&R. Web-based tools were created for clinical use.

conclusionNomogram C&R enables accurate complication risk stratification and supports personalised clinical decision-making in pediatric multiple magnet ingestion. Future prospective validation and integration into clinical pathways are warranted to further establish its role in routine practice.

Indexed as

Foreign BodiesMagnetsNomogramsChildChild, PreschoolFemaleHumansInfantMaleRadiographyRetrospective StudiesRisk AssessmentRisk FactorsChildrenForeign body ingestionNomogramsRadiologyRisk assessment

Identifiers

PMID41239316
PMCPMC12619408

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.