ArticleBMC women's health2025
Pre and Post Menstruation Cognitive Functioning in Women with remenstrual Dysphoric Disorder, Premenstrual Syndrome and Controls: A Quasi Experimental Study.
Article in BMC women's health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Gonadotropins Across the Lifespan: Their role in the Neurodevelopment-Neurodegeneration Continuum.The Yale journal of biology and medicine · 2026Review
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3 authors.
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Abstract
backgroundInconsistent findings regarding the cognitive impact of Premenstrual Syndrome (PMS) and Premenstrual Dysphoric Disorder (PMDD) limit understanding of their effects on women's daily lives. These inconsistencies may arise from neglecting menstrual phase in cognitive assessments. Considering the significant impact of PMS/PMDD on work, academics, and relationships, clarifying their cognitive effects is essential for targeted interventions and improved quality of life. This study investigates the cognitive impacts of these conditions, focusing on the influence of menstrual phase.
methodsUsing a Google Form for initial data collection, 60 participants (mean age 24.47) were categorized into Control, PMS, and PMDD groups based on their responses. Cognitive performance was gauged using the Montreal Cognitive Assessment (MoCA), administered during two distinct menstrual phases: luteal and follicular.
resultsKey findings revealed pronounced cognitive differences across these phases, with the most significant disparities observed in the PMDD group, suggesting a gradient effect where PMDD individuals exhibited the most considerable cognitive shifts (p < .001, η²p = .25). The study's overarching results highlighted a significant divergence in cognitive functioning during the luteal phase, a time historically linked with heightened symptomology in women with PMS and PMDD. Notably, specific cognitive functions, especially language (p < .000) and abstraction (p < .001), showed significant improvement during the follicular phase across all groups (η²p = .25) - a novel finding not assessed in earlier studies.
conclusionsThis study reveals significant cognitive fluctuations across the menstrual cycle, particularly in women with PMDD, and novel improvements in language and abstraction during the follicular phase. Despite limitations, these findings emphasize the importance of considering menstrual phase in assessing and treating women with PMS/PMDD. Further rigorous research is needed to elucidate the neural mechanisms driving these cognitive changes, enabling targeted interventions to improve well-being and functional capacity. The research had its limitations, including a limited sample size, the non-random nature of the sampling method, and potential issues with the tools used for assessments. Despite these constraints, the study provides a foundation for future research, emphasizing the need for a deeper understanding of the neural mechanisms influenced by menstrual phases and offering insights to better support affected women.
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