Evidence map›Paper›PMID 41239239›Full record

ArticleBMC geriatrics2025

The relationship between stroke-related sarcopenia and 3-month neurological outcome in stroke patients: a prospective cohort study.

Aiguo Zhang, Sunwen You, Jianning Xia, Xiangzhi Shao, Xinyu Pu, Jiacheng Zhang, Xinming Wu, Jinyihui Zheng, Dengchong Wu, Bing Chen and 1 more

Abstract read
In one paragraph

Article in BMC geriatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Aiguo ZhangDepartment of Geriatric Medicine, Wenzhou TCM Hospital of Zhejiang Chinese Medical University, Wenzhou, Zhejiang, China.
Sunwen YouDepartment of Rehabilitation, Wenzhou TCM Hospital of Zhejiang Chinese Medical University, No. 9 Jiaowei Road, Lucheng District, Wenzhou, Zhejiang, China.
Jianning XiaDepartment of Rehabilitation, Wenzhou TCM Hospital of Zhejiang Chinese Medical University, No. 9 Jiaowei Road, Lucheng District, Wenzhou, Zhejiang, China.
Xiangzhi ShaoDepartment of Rehabilitation, Wenzhou TCM Hospital of Zhejiang Chinese Medical University, No. 9 Jiaowei Road, Lucheng District, Wenzhou, Zhejiang, China.
Xinyu PuDepartment of Rehabilitation, Wenzhou TCM Hospital of Zhejiang Chinese Medical University, No. 9 Jiaowei Road, Lucheng District, Wenzhou, Zhejiang, China.
Jiacheng ZhangDepartment of Rehabilitation, Wenzhou TCM Hospital of Zhejiang Chinese Medical University, No. 9 Jiaowei Road, Lucheng District, Wenzhou, Zhejiang, China.
Xinming WuDepartment of Rehabilitation, Wenzhou TCM Hospital of Zhejiang Chinese Medical University, No. 9 Jiaowei Road, Lucheng District, Wenzhou, Zhejiang, China.
Jinyihui ZhengDepartment of Rehabilitation, Wenzhou TCM Hospital of Zhejiang Chinese Medical University, No. 9 Jiaowei Road, Lucheng District, Wenzhou, Zhejiang, China.
Dengchong WuDepartment of Rehabilitation, Wenzhou TCM Hospital of Zhejiang Chinese Medical University, No. 9 Jiaowei Road, Lucheng District, Wenzhou, Zhejiang, China.
Bing Chen *Department of Rehabilitation, Wenzhou TCM Hospital of Zhejiang Chinese Medical University, No. 9 Jiaowei Road, Lucheng District, Wenzhou, Zhejiang, China.ORCID http://orcid.org/0000-0001-9389-3327
Lielie Zhu *Department of Rehabilitation, Wenzhou TCM Hospital of Zhejiang Chinese Medical University, No. 9 Jiaowei Road, Lucheng District, Wenzhou, Zhejiang, China. eillie@126.com.ORCID http://orcid.org/0000-0002-7263-3224

Funding

the Wenzhou Municipal Science and Technology Bureau, China Y20220064the Wenzhou Municipal Science and Technology Bureau, China Y2023296Zhejiang Chinese Medical University Affiliated Hospital Research Special Project 2022FSYYZY23Zhejiang Provincial Medical and Health Science and Technology Project 2025KY1516
6 · The paper itself

Abstract

backgroundSarcopenia was initially defined as an age-related decline in muscle mass and function. As sarcopenia has been observed at any age and secondary to many diseases, extending the classical meaning of sarcopenia beyond the age-related phenomenon to the 'disease-related' sarcopenia has been debated recently. Stroke-related sarcopenia occurs secondary to the brain injury and is age-independent, potentially worsening patients' neurological outcomes. We aimed to explore the relationship between stroke-related sarcopenia and 3-month neurological outcome in stroke patients, as well as to evaluate the predictive value of the two main indicators of stroke-related sarcopenia-muscle mass and muscle strength-for adverse neurological outcomes.

methodsA single-centre prospective cohort study of 228 individuals with ischaemic stroke who were admitted for routine rehabilitation treatment, followed up for neurological outcome for 3 months following the onset of the stroke. The muscle mass was expressed by the ratio of appendicular skeletal muscle mass (ASM) to height (Ht) (ASM/Ht

resultsThe prevalence of sarcopenia was 28.9% in all included patients. Compared with the good outcome group, the poor outcome group showed a significantly lower level of ASM/Ht

conclusionsStroke-related sarcopenia is closely related to worse neurological function at the convalescence stage. Higher ASM/Ht

Indexed as

SarcopeniaStrokeAgedAged, 80 and overCohort StudiesFemaleHand StrengthHumansMaleMiddle AgedMuscle StrengthProspective StudiesStroke RehabilitationConvalescence stageNeurological outcomePredictionSarcopeniaStroke

Identifiers

PMID41239239
PMCPMC12619328

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.