Evidence map›Paper›PMID 41239150›Full record

ReviewActa parasitologica2025

The Culture Technology for the Transforming Parasite-Theileria Annulata Schizont-Infected Cells: Past-Present-Perspective.

Quanying Ma, Yuan Han, Yuqing Ma, Xiaoqiang Wang, Zhi Li

Abstract readReview
PubMed Publisher
In one paragraph

Review in Acta parasitologica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Quanying MaSchool of Biological and Pharmaceutical Engineering, Lanzhou Jiaotong University, Lanzhou, 730070, Gansu, China.
Yuan HanQinghai Academy of Animal Sciences and Veterinary Medicine, Qinghai University, Xining, 810016, Qinghai, China.
Yuqing MaSchool of Biological and Pharmaceutical Engineering, Lanzhou Jiaotong University, Lanzhou, 730070, Gansu, China.
Xiaoqiang WangSchool of Biological and Pharmaceutical Engineering, Lanzhou Jiaotong University, Lanzhou, 730070, Gansu, China.
Zhi LiQinghai Academy of Animal Sciences and Veterinary Medicine, Qinghai University, Xining, 810016, Qinghai, China. lizhi19880717@163.com.

Funding

the Educational Technology Innovation of Gansu Province 2023A-042
6 · The paper itself

Abstract

purposeThe cell culture technology for Theileria annulata schizont-infected cells plays a vital role in basic research and control of bovine theileriosis. T. annulata is an intracellular parasite transmitted by some species of ticks.

methodsUnlike other Apicomplexa parasites, T. annulata can infect and transform host B cells, dendritic cells and macrophages, further induce the transformed cells yield some cancer-like phenotypes. The attenuated parasites were obtained through in vitro culture technology, which can effectively prevent T. annulata infection.

resultsThe cell culture has evolved from initial adherent culture to rolling bottle culture and then to suspension culture at present. In addition, the suspension culture has also been upgraded from basic serum-containing culture to serum-free culture.

conclusionThis paper highlights the past, present and perspective about the cell culture technology with T. annulata schizont-infected cells, which will strongly underpin application of T. annulata vaccines and control of the parasite in the future.

Indexed as

Cell Culture TechniquesSchizontsTheileria annulataAnimalsCattleTheileriasisCell culture techniquesSchizont-infected cellsTheileria annulata

Identifiers

PMID41239150

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.