Evidence map›Paper›PMID 41239055›Full record

ReviewTopics in current chemistry (Cham)2025

AgroDrug Conjugates for Sustainable Crop Protection: Molecular Architectures, Mechanisms, and Critical Perspectives.

Giulia Cazzaniga, Roberto Orru, David M Barber, Silvia Gazzola

Abstract readReview
In one paragraph

Review in Topics in current chemistry (Cham), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Giulia CazzanigaDepartment of Science and High Technology, University of Insubria, Via Valleggio 9, 22100, Como, Italy.
Roberto OrruResearch and Development, Weed Control, Bayer AG, Crop Science Division, Industriepark Höchst, 65926, Frankfurt Am Main, Germany.
David M BarberResearch and Development, Weed Control, Bayer AG, Crop Science Division, Industriepark Höchst, 65926, Frankfurt Am Main, Germany.ORCID http://orcid.org/0000-0001-9906-1695
Silvia GazzolaDepartment of Science and High Technology, University of Insubria, Via Valleggio 9, 22100, Como, Italy. s.gazzola@uninsubria.it.ORCID http://orcid.org/0000-0001-6745-3598

Funding

Ministero dell'Università e della Ricerca FISA-2022-00922
6 · The paper itself

Abstract

The agriculture sector faces significant challenges from weeds and pests, exacerbated by climate change. Traditional control methods have led to the emergence of difficult to manage resistant populations, threatening global food security. AgroDrug conjugates (AgDCs) offer a promising approach to enhance agrodrug bioavailability and systemic distribution within plant tissues. This can be accomplished by attaching agrodrugs to molecular carriers such as sugars or amino acids. AgDCs aim to improve targeting and efficiency, while reducing the environmental impact. This review seeks to deliver a thorough and critical analysis of the chemical architectures and underlying mechanisms of action of AgDCs as documented in current scientific literature. Moreover, we highlight advances and knowledge gaps in AgDC design, including metabolic stability, ecological safety, and field-scale performance. Addressing these challenges will be essential to unlock the full potential of AgDCs as next-generation tools for sustainable and resilient crop protection.

Indexed as

AgrochemicalsCrop ProtectionCrops, AgriculturalAgrochemicalsAgrochemicalsAgroDrug conjugatesAgrodrugsCrop protectionSustainable agriculture

Identifiers

PMID41239055
PMCPMC12618302

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.