ArticleSleep & breathing = Schlaf & Atmung2025
Impact of comorbid obstructive sleep apnea on sleep efficiency and architecture in patients with periodic limb movements: an exploratory study.
Article in Sleep & breathing = Schlaf & Atmung, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Periodic limb movements of sleep: A comparison of REM and NREM.Sleep medicine: X · 2026Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPeriodic limb movements during sleep (PLMS) and obstructive sleep apnea syndrome (OSAS) are common sleep disorders that affect sleep quality. Their combined impact on sleep architecture and overall sleep disruption remains uncertain.
objectiveAssess whether the presence of comorbid OSAS in patients with PLMD further affects sleep efficiency and architecture compared to patients with PLMD alone.
methodsA descriptive, comparative cross-sectional study was conducted on 70 patients diagnosed with PLMD (periodic limb movement index > 15/h), identified through polysomnographic (PSG) recordings (Levels 1 and 2) between January 2021 to June 2023 at the Sleep Laboratory of the Hospital Universitário de São João, Porto, Portugal. Patients were divided into two groups: Group 1 (n = 52) with concomitant OSAS and PLMD, and Group 2 (n = 18) with PLMD alone. Demographic, clinical, and polysomnographic data were analyzed. Between-group comparisons were performed using appropriate statistical tests, with a significance threshold of p < 0.05.
resultsNo statistically significant differences were observed in sleep efficiency (p = 0.16), total sleep time (p = 0.42), or PLMS index (p = 0.98) between groups. However, significant differences (p < 0,001) were observed in the apnea-hypopnea index, oxygen desaturation index, and respiratory arousal index. These findings suggest that OSAS does not exacerbate sleep fragmentation or reduce sleep efficiency beyond the disruption attributed to PLMS alone.
conclusionThe presence of OSAS in patients with PLMD does not significantly worsen sleep fragmentation, efficiency, or architecture beyond the disruption caused by PLMD alone. Targeted therapeutic strategies should focus on managing PLMS-related disturbances independently of OSAS coexistence.
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