Trial reportCerebellum (London, England)2025
Effect of Dynamic Balance Training Combined with Different Intensities of Cerebellar Transcranial Direct Current Stimulation in People with Parkinson's Disease: a Randomized Clinical Trial.
Trial report in Cerebellum (London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
Impaired balance is one of the most disabling symptoms in people with Parkinson's disease (PwPD). While motor intervention can improve balance control, its effects might be enhanced through cerebellar transcranial direct current stimulation (ctDCS). However, the optimal stimulation intensity remains a point open to investigation. To compare the effects of dynamic balance training combined with different intensities of anodal ctDCS on improvements in body balance and modulation of prefrontal cortex (PFC) activation in PwPD. Thirty-three PwPD were randomized into three groups varying in the intensity of ctDCS (4 mA, 2 mA, Sham) in a double-blind, sham-controlled design. Participants underwent 6 sessions of progressively challenging dynamic balance training combined with ctDCS/sham. Balance improvements were assessed through center of pressure excursion in quiet standing and dynamic transfer tasks. Training-related effects were also evaluated in PFC activation using functional near-infrared spectroscopy. Balance training combined with ctDCS led to higher improvements in balance compared to training without cerebellar stimulation. The 4 mA stimulation intensity led to greater balance gains than the 2 mA and sham stimulation across all transfer task categories assessed. Balance training led to decreased PFC activation, with no detectable differences between the groups. Six sessions of dynamic balance training combined with the ctDCS intensity of 4 mA resulted in superior improvement of balance in PwPD. Balance training led to decreased PFC activation in the performance of different transfer tasks regardless of the ctDCS condition. Brazilian Registry of Clinical Trials (ReBEC) URL: ensaiosclinicos.gov.br/rg/RBR-7yt65zp, data of registration 08/12/2024, retrospectively registered.
Indexed as
Identifiers
41239034What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.