Evidence map›Paper›PMID 41238400›Full record

ArticleAJNR. American journal of neuroradiology2026

Impact of Spatial Resolution on CT Imaging of Middle Ear Prostheses: Comparison of Photon-Counting and Energy-Integrating Detectors.

Maryam Sadeghian, John C Benson, Paul J Farnsworth, John I Lane, Kevin J Treb, Karl R Khandalavala, Eric E Babajanian, Michael R Bruesewitz, Joseph R Swicklik, Cynthia H McCollough and 2 more

Abstract readComparative Study
In one paragraph

Article in AJNR. American journal of neuroradiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Photon-counting detector computed tomography for temporal bone: does higher resolution matter?Current opinion in otolaryngology & head and neck surgery · 2026
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Maryam SadeghianFrom the Department of Radiology (M.S., J.C.B., P.J.F., J.I.L., K.J.T., M.R.B., J.R.S., C.H.M., S.L.), Mayo Clinic, Rochester, Minnesota.ORCID https://orcid.org/0000-0003-3663-6011
John C BensonFrom the Department of Radiology (M.S., J.C.B., P.J.F., J.I.L., K.J.T., M.R.B., J.R.S., C.H.M., S.L.), Mayo Clinic, Rochester, Minnesota.ORCID https://orcid.org/0000-0002-4038-5422
Paul J FarnsworthFrom the Department of Radiology (M.S., J.C.B., P.J.F., J.I.L., K.J.T., M.R.B., J.R.S., C.H.M., S.L.), Mayo Clinic, Rochester, Minnesota.ORCID https://orcid.org/0000-0002-3955-6722
John I LaneFrom the Department of Radiology (M.S., J.C.B., P.J.F., J.I.L., K.J.T., M.R.B., J.R.S., C.H.M., S.L.), Mayo Clinic, Rochester, Minnesota.ORCID https://orcid.org/0000-0001-5874-633X
Kevin J TrebFrom the Department of Radiology (M.S., J.C.B., P.J.F., J.I.L., K.J.T., M.R.B., J.R.S., C.H.M., S.L.), Mayo Clinic, Rochester, Minnesota.
Karl R KhandalavalaDepartment of Otolaryngology-Head and Neck Surgery (K.R.K., E.E.B., M.L.C.), Mayo Clinic, Rochester, Minnesota.
Eric E BabajanianDepartment of Otolaryngology-Head and Neck Surgery (K.R.K., E.E.B., M.L.C.), Mayo Clinic, Rochester, Minnesota.
Michael R BruesewitzFrom the Department of Radiology (M.S., J.C.B., P.J.F., J.I.L., K.J.T., M.R.B., J.R.S., C.H.M., S.L.), Mayo Clinic, Rochester, Minnesota.
Joseph R SwicklikFrom the Department of Radiology (M.S., J.C.B., P.J.F., J.I.L., K.J.T., M.R.B., J.R.S., C.H.M., S.L.), Mayo Clinic, Rochester, Minnesota.
Cynthia H McColloughFrom the Department of Radiology (M.S., J.C.B., P.J.F., J.I.L., K.J.T., M.R.B., J.R.S., C.H.M., S.L.), Mayo Clinic, Rochester, Minnesota.ORCID https://orcid.org/0000-0002-5346-332X
Matthew L CarlsonDepartment of Otolaryngology-Head and Neck Surgery (K.R.K., E.E.B., M.L.C.), Mayo Clinic, Rochester, Minnesota.ORCID https://orcid.org/0000-0002-4925-8593
Shuai LengFrom the Department of Radiology (M.S., J.C.B., P.J.F., J.I.L., K.J.T., M.R.B., J.R.S., C.H.M., S.L.), Mayo Clinic, Rochester, Minnesota Leng.Shuai@mayo.edu.ORCID https://orcid.org/0000-0002-6453-9481

Funding

High-resolution in vivo imaging of inner ear using photon-counting-detector computed tomography and artificial intelligenceR01DC022228 · NIDCD · MAYO CLINIC ROCHESTER · PI Matthew L Carlson, Shuai Leng · 2025 to 2026
$1.5M
NIDCD NIH HHS R01 DC022228
6 · The paper itself

Abstract

background and purposeCT imaging of submillimeter middle ear prostheses-vital for postsurgery treatment-requires high spatial resolution. This study evaluated the impact of spatial resolution for the visualization of prostheses using photon-counting detector (PCD) CT, energy-integrating detector (EID) CT, and EID-CT with attenuating comb filters. MATERIALS AND

methodsTwenty-one middle ear prostheses of different makes were placed within a head phantom and scanned on a PCD-CT (NAEOTOM Alpha), 2 dual-source CTs with comb filters (Force and Flash), and a dual-layer CT without comb filter (7500). Scanning and reconstruction followed clinical temporal bone protocols for each scanner, with a matched 120 kV and 80 mm FOV; sharp kernels/algorithms of Qr89, Ur77, Ur77, and YD; and minimal allowable slice thickness of 0.2, 0.4, 0.5, and 0.67 mm, respectively. Qualitative assessments were performed, including visual inspection, volume rendering, a blind reader study, and quantitative assessments using line profiles, and full width at half maximum (FWHM). One prosthesis was implanted in human cadaver head and scanned on a PCD-CT (NAEOTOM Alpha), a third-generation dual-source (Force), and a dual-layer CT (7500) following the same phantom study protocols. Image quality was compared among the scanners.

resultsPCD-CT provided images with the highest spatial resolution, allowing clinically relevant assessment of prosthesis position. EID-CT scanners with comb filters provided good results, with noticeable loss of detail, while EID-CT without a comb filter showed substantial resolution loss. These findings were consistent across readers (Kendall W = 0.89;

conclusionsPCD-CT provided dose-efficient, accurate evaluation of ossicular prostheses, without the degradation of submillimeter structures, while maintaining lower dose and noise.

Indexed as

Ear, MiddleOssicular ProsthesisTomography, X-Ray ComputedHumansPhantoms, ImagingPhotonsReproducibility of ResultsSensitivity and Specificity

Identifiers

PMID41238400
PMCPMC12853312

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.