ArticleJACC. Case reports2025
High-Sensitivity vs Conventional Cardiac Troponin T in Non-ACS Hospitalized Patients: Impact on Resource Use and Outcomes.
Article in JACC. Case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
9 authors.
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Abstract
backgroundHigh-sensitivity cardiac troponin T (hs-cTnT) enables earlier and more sensitive detection of myocardial injury compared with conventional troponin assays. Although extensively studied in acute coronary syndrome (ACS), its role in non-ACS hospitalized populations remains less clear. PROJECT RATIONALE: In patients admitted without ACS, hs-cTnT may improve diagnostic efficiency and reduce unnecessary testing, but it may also increase detection of ambiguous troponin elevations, leading to resource overuse. Assessing its real-world impact is therefore essential. PROJECT SUMMARY: We conducted a retrospective study of 520 hospitalized patients at St Mary's General Hospital (January-May 2023). Propensity score-matched cohorts (260 hs-cTnT vs 260 cTnT) were compared; hs-cTnT use was associated with shorter length of stay (7.3 vs 10.9 days, P < 0.01), reduced echocardiography (76.9% vs 88.8%, P = 0.005), and fewer electrophysiology procedures (2.3% vs 6.5%, P = 0.033), with no group differences in mortality. TAKE-HOME MESSAGE: Findings indicated that hs-cTnT streamlines inpatient care, reduces resource use, and maintains safety, supporting its broader adoption beyond ACS.
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