Article in Journal of the American Chemical Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Manas JoshiDepartment of Chemistry, Boston College, Chestnut Hill, Massachusetts 02467, United States.ORCID 0000-0002-5989-776X
Soichiro MoriSkaggs Graduate School of Chemical and Biological Sciences, Scripps Research, Jupiter, Florida 33458, United States.
Abhishek ChatterjeeDepartment of Chemistry, Boston College, Chestnut Hill, Massachusetts 02467, United States.ORCID 0000-0002-6231-5302
Ben ShenSkaggs Graduate School of Chemical and Biological Sciences, Scripps Research, Jupiter, Florida 33458, United States.ORCID 0000-0002-9750-5982
Matthew D DisneySkaggs Graduate School of Chemical and Biological Sciences, Scripps Research, Jupiter, Florida 33458, United States.ORCID 0000-0001-8486-1796
Masayuki WasaSkaggs Graduate School of Chemical and Biological Sciences, Scripps Research, Jupiter, Florida 33458, United States.ORCID 0000-0002-3309-9129
Funding
Mining Actinomycetal Genomes for Natural Product Discovery and BiosynthesisR35GM134954 · NIGMS · UNIVERSITY OF FLORIDA · PI Ben Shen · 2020 to 2026
$5.1M
Targeted degradation of RNAs by using small moleculesR01CA249180 · NCI · UNIVERSITY OF FLORIDA · PI Matthew D Disney · 2020 to 2026
$4.8M
Novel Enediyne-Based Antibody-Drug Conjugates for CancersR01CA204484 · NCI · UNIVERSITY OF FLORIDA · PI Natarajan Muthusamy, Ben Shen · 2017 to 2026
$4.6M
A genetically encoded toolset to decipher the biology of post-translational modifications in the mammalian proteomeR35GM136437 · NIGMS · BOSTON COLLEGE · PI Abhishek Chatterjee · 2020 to 2026
$4.0M
Catalytic and Stereoselective C-C-Heteroatom Bond Forming ReactionsR35GM128695 · NIGMS · UNIVERSITY OF FLORIDA · PI Masayuki Wasa · 2018 to 2026
$3.8M
Bruker Avance III HD 600 MHz NMR spectrometerS10OD021550 · OD · SCRIPPS FLORIDA · PI KOJETIN, DOUGLAS · 2017 to 2017
$600k
Bruker D8 VENTURE DiffractometerS10OD030360 · OD · BOSTON COLLEGE · PI LI, BO · 2022 to 2022
$428k
Biosynthesis of the Leinamycin Family of Natural Products: Mechanistic Studies and Chemoenzymatic Analog SynthesisF32GM133114 · NIGMS · UNIVERSITY OF FLORIDA · PI STEELE, ANDREW · 2019 to 2021
The ability to introduce functional groups suitable for bioconjugation into natural products and pharmaceuticals in an efficient, chemo- and site-selective manner is critical for advancing drug discovery, biological chemistry, and targeted therapy. Late-stage C-H functionalization enables direct structural diversification of lead compounds, but broader application is constrained by the scarcity of catalysts that selectively activate relatively inert C-H bonds in polyfunctional drug compounds. Here, we report a photoinduced, flavin-catalyzed method that installs bioconjugation handles on a broad range of bioactive
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.