Evidence map›Paper›PMID 41237172›Full record

Trial reportPloS one2025

Perceived effectiveness of messages to address cervical cancer screening barriers: An online experiment.

Sarah M Halvorson-Fried, Isabella C A Higgins, Melissa B Gilkey, Allison J Lazard, Marissa G Hall

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sarah M Halvorson-FriedDepartment of Health Behavior, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.ORCID https://orcid.org/0009-0000-0361-5439
Isabella C A HigginsDepartment of Health Behavior, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.ORCID https://orcid.org/0000-0003-0241-2378
Melissa B GilkeyDepartment of Health Behavior, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
Allison J LazardCancer Prevention and Control, Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
Marissa G HallDepartment of Health Behavior, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.

Funding

Cancer Control Education ProgramT32CA057726 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Melissa B Gilkey, Melissa A. Troester · 2017 to 2026
$3.7M
Training Program in Cancer Prevention and Control for Priority PopulationsT32CA225617 · NCI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Guy H Montgomery, JUAN P WISNIVESKY · 2018 to 2026
$2.6M
NCI NIH HHS T32 CA057726NCI NIH HHS T32 CA225617
6 · The paper itself

Abstract

introductionCervical cancer is almost entirely preventable through vaccination and screening, but screening rates still lag targets. Communication campaigns can encourage screening; however, the types of message content that are most effective are unknown.

methodsWe conducted an online randomized experiment testing messages within four themes aligned with previously identified screening barriers: cancer fatalism, inconvenience, lack of knowledge about risk factors, and unawareness of screening guidelines. A national convenience sample of US participants aged 21-65 years and assigned female at birth (n = 1,536) viewed one of three messages from each theme assigned at random and one control message in random order. We measured perceived effectiveness to encourage cervical cancer screening, anticipated social interactions, and self-reported learning. Mixed-effects linear models examined the impact of message theme on each outcome on a scale from 1 (low) to 5 (high).

resultsAll four barrier-focused themes encouraged cervical cancer screening more than the control (perceived message effectiveness mean and standard deviation: cancer fatalism = 3.44 (1.21); convenience = 3.43 (1.23); risk factors = 3.25 (1.23); screening guidelines = 3.44 (1.19); control message = 2.45 (1.35), p < .001). Barrier-focused messages similarly outperformed the control on anticipated social interactions and self-reported learning (all p < .001). Messages were less effective for participants who had never been screened or were out-of-date. However, regardless of screening status, barrier-focused messages outperformed the control.

conclusionsMessages targeting known barriers to cervical cancer screening were perceived as more effective than a control message. These messages could increase cervical cancer screening rates if used in interventions at scale.

Indexed as

Early Detection of CancerUterine Cervical NeoplasmsAdultAgedFemaleHealth Knowledge, Attitudes, PracticeHealth PromotionHumansInternetMiddle AgedYoung Adult

Identifiers

PMID41237172
PMCPMC12617949

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.