Evidence map›Paper›PMID 41236925›Full record

ArticleVirulence2025

Protoporphyrin IX targets viral spike glycoproteins to inactivate Akabane virus.

Ping Li, Dajun Zhang, Mengna Deng, Dengshuai Zhao, Yuanhang Zhang, Shikai Cai, Wenda Zong, Canyuan Li, Miaomiao Zhang, Zhihao Li and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Virulence, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Ping LiGuangdong Provincial Key Laboratory of Animal Molecular Design and Precise Breeding, School of Animal Science and Technology, Foshan University, Foshan, China.ORCID 0009-0007-9149-0939
Dajun ZhangGuangdong Provincial Key Laboratory of Animal Molecular Design and Precise Breeding, School of Animal Science and Technology, Foshan University, Foshan, China.
Mengna DengGuangdong Provincial Key Laboratory of Animal Molecular Design and Precise Breeding, School of Animal Science and Technology, Foshan University, Foshan, China.
Dengshuai ZhaoGuangdong Provincial Key Laboratory of Animal Molecular Design and Precise Breeding, School of Animal Science and Technology, Foshan University, Foshan, China.ORCID 0009-0008-2613-0598
Yuanhang ZhangGuangdong Provincial Key Laboratory of Animal Molecular Design and Precise Breeding, School of Animal Science and Technology, Foshan University, Foshan, China.ORCID 0009-0004-7837-1634
Shikai CaiGuangdong Provincial Key Laboratory of Animal Molecular Design and Precise Breeding, School of Animal Science and Technology, Foshan University, Foshan, China.
Wenda ZongGuangdong Provincial Key Laboratory of Animal Molecular Design and Precise Breeding, School of Animal Science and Technology, Foshan University, Foshan, China.
Canyuan LiGuangdong Provincial Key Laboratory of Animal Molecular Design and Precise Breeding, School of Animal Science and Technology, Foshan University, Foshan, China.
Miaomiao ZhangGuangdong Provincial Key Laboratory of Animal Molecular Design and Precise Breeding, School of Animal Science and Technology, Foshan University, Foshan, China.
Zhihao LiGuangdong Provincial Key Laboratory of Animal Molecular Design and Precise Breeding, School of Animal Science and Technology, Foshan University, Foshan, China.
Youbao ZhaoCollege of Veterinary Medicine, Henan Agricultural University, Zhengzhou, China.
Limei QinGuangdong Provincial Key Laboratory of Animal Molecular Design and Precise Breeding, School of Animal Science and Technology, Foshan University, Foshan, China.
Han GaoGuangdong Provincial Key Laboratory of Animal Molecular Design and Precise Breeding, School of Animal Science and Technology, Foshan University, Foshan, China.ORCID 0000-0002-2718-6349
Keshan ZhangGuangdong Provincial Key Laboratory of Animal Molecular Design and Precise Breeding, School of Animal Science and Technology, Foshan University, Foshan, China.ORCID 0009-0002-0306-0327

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Akabane virus (AKAV), an emerging arthropod-borne

Indexed as

Antiviral AgentsOrthobunyavirusProtoporphyrinsSpike Glycoprotein, CoronavirusVirus InactivationAnimalsBunyaviridae InfectionsMiceVirus ReplicationAntiviral Agentsprotoporphyrin IXProtoporphyrinsSpike Glycoprotein, CoronavirusAkabane virus (AKAV)Gc proteininactivationprotoporphyrin IX (PPIX)

Identifiers

PMID41236925
PMCPMC12622351

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.