Evidence map›Paper›PMID 41236856›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2026

Early Detection of Chemotherapy-Induced Glucose Metabolic Alterations in Bladder Carcinoma Using Deuterium (

Lingmin Kong, Ganghan Yang, Bei Weng, Zhihua Wen, Joshua D Kaggie, Qian Cai, Qian Wan, Cuien Zheng, Feng Du, Ye Li and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Lingmin KongDepartment of Radiology, The First Affiliated Hospital, Sun Yat-sen University, 58 Zhongshan Road 2, Guangzhou, Guangdong, 510080, P. R. China.
Ganghan YangThe School of Electronics and Information Engineering, Harbin Institute of Technology, Harbin, 150001, P. R. China.
Bei WengDepartment of Radiology, The First Affiliated Hospital, Sun Yat-sen University, 58 Zhongshan Road 2, Guangzhou, Guangdong, 510080, P. R. China.
Zhihua WenDepartment of Radiology, The First Affiliated Hospital, Sun Yat-sen University, 58 Zhongshan Road 2, Guangzhou, Guangdong, 510080, P. R. China.
Joshua D KaggieDepartment of Radiology, University of Cambridge, Cambridge, CB2 0QQ, UK.
Qian CaiDepartment of Radiology, The First Affiliated Hospital, Sun Yat-sen University, 58 Zhongshan Road 2, Guangzhou, Guangdong, 510080, P. R. China.
Qian WanPaul C. Lauterbur Research Center for Biomedical Imaging, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong, 518055, P. R. China.
Cuien ZhengPaul C. Lauterbur Research Center for Biomedical Imaging, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong, 518055, P. R. China.
Feng DuPaul C. Lauterbur Research Center for Biomedical Imaging, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong, 518055, P. R. China.
Ye LiPaul C. Lauterbur Research Center for Biomedical Imaging, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong, 518055, P. R. China.
Xin LiuPaul C. Lauterbur Research Center for Biomedical Imaging, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong, 518055, P. R. China.
Ferdia A GallagherDepartment of Radiology, University of Cambridge, Cambridge, CB2 0QQ, UK.
Yan GuoDepartment of Radiology, The First Affiliated Hospital, Sun Yat-sen University, 58 Zhongshan Road 2, Guangzhou, Guangdong, 510080, P. R. China.
Shi-Ting FengDepartment of Radiology, The First Affiliated Hospital, Sun Yat-sen University, 58 Zhongshan Road 2, Guangzhou, Guangdong, 510080, P. R. China.
Chao ZouPaul C. Lauterbur Research Center for Biomedical Imaging, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong, 518055, P. R. China.
Huanjun WangDepartment of Radiology, The First Affiliated Hospital, Sun Yat-sen University, 58 Zhongshan Road 2, Guangzhou, Guangdong, 510080, P. R. China.ORCID https://orcid.org/0000-0001-9089-7736

Funding

Basic and Applied Basic Research Foundation of Guangdong Province, China 2022B1515120068Key Laboratory for Magnetic Resonance and Multimodality Imaging of Guangdong Province 2023B1212060052National Key R&D Program of China 2023YFC3402802National Natural Science Foundation of China 82271958National Natural Science Foundation of China 82371911National Natural Science Foundation of China 82372075National Natural Science Foundation of China 82402415National Natural Science Foundation of China 82471948National Natural Science Foundation of China 82572352Natural Science Outstanding Youth Fund Project of Guangdong province, China 2024B1515020061Project on Global Common Challenges of the Chinese Academy of Sciences 321GJHZ2022081GCStrategic Priority Research Program of the Chinese Academy of Sciences XDB0930000Youth Innovation Promotion Association of CAS Y2021098Youth Medical Innovation and Practice Research Program of Guangzhou 2023QNYXYB009
6 · The paper itself

Abstract

Deuterium metabolic imaging (DMI) is a promising noninvasive technique for assessing tumor metabolism, yet its application in bladder cancer (BCa) remains unexplored. This study presents the first demonstration of DMI for evaluating therapeutic response in BCa through in vitro and in vivo experiments. Two types of deuterium-labeled glucose tracers, [6,6'-

Indexed as

Antineoplastic AgentsDeuteriumGlucoseUrinary Bladder NeoplasmsAnimalsCell Line, TumorFemaleGlycolysisHumansMiceMice, NudeAntineoplastic AgentsDeuteriumGlucosebladder tumorchemotherapydeuteriummetabolism

Identifiers

PMID41236856
PMCPMC12866816

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.