Evidence map›Paper›PMID 41236658›Full record

ArticleEuropean radiology2026

Added value and clinical impact of second-opinion subspecialist radiologist interpretations of baseline rectal MRI in patients with rectal cancer.

Jennifer S Golia Pernicka, Tae-Hyung Kim, Stephanie Nougaret, David D B Bates, Maria El Homsi, J Louis Fuqua, Natalie Gangai, Natally Horvat, Emmanouil Pappou, Viktoriya Paroder and 3 more

Abstract read
In one paragraph

Article in European radiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Jennifer S Golia Pernicka *Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA. goliapej@mskcc.org.ORCID http://orcid.org/0000-0002-1076-7948
Tae-Hyung Kim *Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Stephanie NougaretDepartment of Radiology, Montpellier Cancer Institute, Montpellier, France.
David D B BatesDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Maria El HomsiDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
J Louis FuquaDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Natalie GangaiDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Natally HorvatDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Emmanouil PappouDepartment of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Viktoriya ParoderDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Maria WidmarDepartment of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Iva PetkovskaDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Marc J GollubDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

objectivesTo evaluate the completeness and discordance of outside rectal MRI initial staging reports compared to second-opinion reviews, and to assess the potential clinical impact of major discordance on treatment decisions in patients with rectal adenocarcinoma. MATERIALS AND

methodsA retrospective analysis of outside rectal MRI reviews submitted for second-opinion interpretation by subspecialized radiologists from June 2014-March 2020 was conducted. Outside and second review reports were compared side-by-side; cases with discordance (and those with major discordance, i.e., may alter treatment, particularly) were identified. Two colorectal surgeons, blinded to report origins, reviewed cases with major discordance to evaluate their theoretical impact on patient management and rated their confidence level of the reports on a five-point Likert scale (1=lowest confidence).

resultsIn 461 patients (median age, 57 years [IQR: 49-67]; 274 male), compared to outside reviews, second reviews demonstrated improved report completeness across tumor characteristics, local extent, and nodal/metastatic disease clinical staging categories. The largest reporting gaps were in tumor morphology (66.4%, 306/461 vs. 98.7%, 455/461) and extramural venous invasion (29.1%, 134/461 vs. 93.9%, 433/461). Overall, 53.8% (248/461) of cases showed discordance, with 56.5% (140/248) classified as major. In this subset, second reviews led to fewer cases with insufficient information, e.g., 18.6% (26/140) to 7.1% (10/140) for Surgeon 1, and changes in surgical planning in 38.1-46.3% (43/113 to 44/95) of patients. Surgeons rated reports from second reviews with higher confidence scores (median, 4 vs. 2-3, p < 0.001).

conclusionsSecond-opinion reviews may impact patient care and improve surgeons' confidence for treatment planning. KEY POINTS: Question Do subspecialist radiologist second-opinion reviews improve rectal MRI report completeness and affect treatment decisions in rectal adenocarcinoma staging? Findings While outside reviews often under-reported key imaging findings, second reviews improved report completeness, which led to increased confidence by our surgeons in treatment planning. Clinical relevance These findings underscore the value of expert interpretation and highlight the need for optimized MRI protocols and broader adoption of structured reporting in rectal cancer staging.

Indexed as

AdenocarcinomaMagnetic Resonance ImagingRectal NeoplasmsReferral and ConsultationAgedFemaleHumansMaleMiddle AgedNeoplasm StagingRadiologistsRetrospective StudiesRectal adenocarcinomaRectal neoplasmsSecond-opinionTreatment planningTumor staging

Identifiers

PMID41236658
PMCPMC12895060

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.