Evidence map›Paper›PMID 41236581›Full record

ReviewCurrent cardiology reports2025

Alteration of Essential Cell Function by Ultrasound-Targeted Microbubble Cavitation.

Anurag N Paranjape, Xucai Chen, Flordeliza S Villanueva

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current cardiology reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Anurag N ParanjapeCenter for Ultrasound Molecular Imaging and Therapeutics, Heart and Vascular Institute, University of Pittsburgh, Pittsburgh, PA, 15213, USA.
Xucai ChenCenter for Ultrasound Molecular Imaging and Therapeutics, Heart and Vascular Institute, University of Pittsburgh, Pittsburgh, PA, 15213, USA.
Flordeliza S VillanuevaCenter for Ultrasound Molecular Imaging and Therapeutics, Heart and Vascular Institute, University of Pittsburgh, Pittsburgh, PA, 15213, USA. villanuevafs@upmc.edu.

Funding

Biological and Physical Mechanisms of ultrasound/microbubble-mediated therapeutic gene delivery across the endothelial barrierR01EB026966 · NIBIB · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI VILLANUEVA, FLORDELIZA S · 2018 to 2021
$3.0M
NIH HHS R01EB026966
6 · The paper itself

Abstract

purpose of reviewUltrasound-targeted microbubble cavitation (UTMC) has emerged as a transformative non-invasive technology in diagnostic imaging, therapy, and targeted gene and drug delivery. As UTMC advances toward clinical translation, understanding its impact on fundamental cellular functions is essential. RECENT

findingsRecent studies on UTMC have provided insights into its effects on biological processes. These include transient membrane opening and resealing (sonoporation), calcium ion (Ca

Indexed as

MicrobubblesCalciumDrug Delivery SystemsHumansCalciumBioeffectsCalciumDrug deliveryEndothelial cellsMicrobubblesUltrasound

Identifiers

PMID41236581

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.