ArticleVeterinary medicine and science2025
Efficacy of Dietary Cottonseed Bioactive Peptides Compared to Diclazuril or Salinomycin on Reducing Adverse Effects of Coccidiosis Challenge in Broiler Chickens.
Article in Veterinary medicine and science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Effects of Immunologically Active Peptides on Growth Performance, Meat Quality, Antioxidant Capacity, and Ileum Inflammation in Broilers.Veterinary sciences · 2026Article
- Efficacy of Dietary Cottonseed Bioactive Peptides Compared to Diclazuril or Salinomycin on Reducing Adverse Effects of Coccidiosis Challenge in Broiler Chickens.Veterinary medicine and science · 2025Article
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4 authors.
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Abstract
backgroundBioactive peptides present antimicrobial, antioxidative and immunomodulatory activities with beneficial effects on broiler chickens.
objectivesThis experiment was conducted to examine the influence of dietary supplemental cottonseed bioactive peptides (CBP) on growth performance, oocysts per gram of faeces (OPG), intestinal morphology, immune responses and interleukin-6 (IL-6) gene expression in broilers exposed to coccidial infection.
methodsA total of 420 broiler chicks (Ross 308) were assigned to seven dietary treatments in a completely randomized design during 10-45 days of age. Experimental treatments included: (1) CON+, broiler chickens without challenge; (2) CON-, birds challenged with coccidiosis; (3-5) the CON- birds fed diets containing 4 g/kg, 5 g/kg or 6 g/kg CBP, respectively; (6) the CON- birds fed diets containing 0.2 g/kg diclazuril; (7) the CON- birds fed diets containing 0.5 g/kg salinomycin.
resultsInfection alleviated daily feed intake and growth of broilers fed a basal diet during 31-38 days of age (p < 0·05), which ameliorated after supplementation of 6 g/kg CBP (p < 0.05). Dietary 4 or 6 g/kg CBP, diclazuril or salinomycin compensated for the impairment in the feed conversion ratio of Eimeria spp. challenged broilers during 31-45 days of age (p < 0.05). Coccidiosis challenge increased OPG; however, the OPG value decreased when the diet contained CBP or anti-coccidiosis drugs (p < 0.05). Antibody titer against sheep red blood cells improved in challenged birds fed 6 g/kg CBP (p < 0.05).
conclusionsDietary CBP decreased the negative effects of coccidiosis, whereby supplemented birds had similar immune responses or even better growth performance than birds receiving anticoccidials.
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