Evidence map›Paper›PMID 41236438›Full record

SynthesisJournal of neurochemistry2025

Touchscreen and Translational Cognition: A Systematic Review of Trials in Humans and Rodents.

Tamires Coelho Martins, Renata Maria Silva Santos, Rayany Karolyny da Silva Andrade, André Soares da Silva, Felipe Baptista Brunheroto, Isabella Paula Gomes Rocha, Vitória Carrazza Gambogi Loureiro, Yuri Cristelli de Sousa Silva, Ana Caroline Nogueira Souza, Eduardo de Souza Nicolau and 2 more

Abstract readSystematic Review
In one paragraph

Synthesis in Journal of neurochemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Tamires Coelho MartinsCenter for Technology in Molecular Medicine (CTMM), Federal University of Minas Gerais (UFMG), Belo Horizonte, Minas Gerais, Brazil.ORCID 0009-0001-2544-0972
Renata Maria Silva SantosPost-graduate Program in Molecular Medicine, Federal University of Minas Gerais (UFMG), Belo Horizonte, Minas Gerais, Brazil.ORCID 0000-0001-5737-7712
Rayany Karolyny da Silva AndradePost-graduate Program in Molecular Medicine, Federal University of Minas Gerais (UFMG), Belo Horizonte, Minas Gerais, Brazil.ORCID 0009-0008-3145-6410
André Soares da SilvaCenter for Technology in Molecular Medicine (CTMM), Federal University of Minas Gerais (UFMG), Belo Horizonte, Minas Gerais, Brazil.ORCID 0000-0001-8636-9586
Felipe Baptista BrunherotoCenter for Technology in Molecular Medicine (CTMM), Federal University of Minas Gerais (UFMG), Belo Horizonte, Minas Gerais, Brazil.ORCID 0000-0002-1986-4453
Isabella Paula Gomes RochaCenter for Technology in Molecular Medicine (CTMM), Federal University of Minas Gerais (UFMG), Belo Horizonte, Minas Gerais, Brazil.ORCID 0009-0007-1010-6596
Vitória Carrazza Gambogi LoureiroCenter for Technology in Molecular Medicine (CTMM), Federal University of Minas Gerais (UFMG), Belo Horizonte, Minas Gerais, Brazil.ORCID 0009-0007-6941-4446
Yuri Cristelli de Sousa SilvaCenter for Technology in Molecular Medicine (CTMM), Federal University of Minas Gerais (UFMG), Belo Horizonte, Minas Gerais, Brazil.ORCID 0009-0002-9861-0642
Ana Caroline Nogueira SouzaPost-graduate Program in Molecular Medicine, Federal University of Minas Gerais (UFMG), Belo Horizonte, Minas Gerais, Brazil.ORCID 0000-0002-5938-3486
Eduardo de Souza NicolauPost-graduate Program in Molecular Medicine, Federal University of Minas Gerais (UFMG), Belo Horizonte, Minas Gerais, Brazil.ORCID 0000-0002-7500-8387
Débora Marques MirandaDepartment of Pediatrics, Federal University of Minas Gerais (UFMG), Belo Horizonte, Minas Gerais, Brazil.ORCID 0000-0002-7081-8401
Marco Aurélio Romano-SilvaDepartment of Psychiatry, Federal University of Minas Gerais (UFMG), Belo Horizonte, Minas Gerais, Brazil.ORCID 0000-0002-6558-4639

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)FAPEMIGFundação de Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
6 · The paper itself

Abstract

The implementation of touchscreen platforms in co-clinical trials for rodents (i.e., mice and rats) and humans to assess cognitive functions presents an opportunity to overcome barriers present in conventional clinical trials. To better visualize the progress made in this area, this review proposes a systematic synthesis of the comparability of touchscreen cognitive assessment studies applied to both humans and rodents in a co-clinical framework. To accomplish this objective the Ovid, PubMed, Scopus and ScienceDirect databases were searched, in English, and without publication date limit and registered on the International Prospective Register of Systematic Review (PROSPERO) under the number CRD420250650537. The screening resulted in 5 cross-sectional studies and 1 randomized controlled trial (RCT) included, which were assessed for methodological quality and risk of bias using the Joanna Briggs Institute (JBI) critical appraisal tools. The data acquired in this review reinforce the potential of touchscreen platforms for cognitive assessment across human and rodent models. Behavioral flexibility and visuospatial cognition excelled in terms of comparability. The scarcity of studies and methodological diversity represent significant gaps in the field. Regardless, the available data highlight important opportunities for advancing translational research in cognition with a co-clinical approach.

Indexed as

CognitionTranslational Research, BiomedicalAnimalsHumansMiceRandomized Controlled Trials as TopicRatsRodentiaco‐clinicalcognitionhumanrodentsystematic reviewtouchscreen platform

Identifiers

PMID41236438
PMCPMC12617393

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.