ArticleDermatology practical & conceptual2025
Risk Factors and Epidemiology of Acne Severity and Acne Scar Development: A Comprehensive Clinical Study.
Article in Dermatology practical & conceptual, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Comparison of a 755-nm picosecond laser and a 1565-nm nonablative fractional laser for the treatment of atrophic acne scars: a 20-week prospective, randomized, split-face clinical study.Lasers in medical science · 2026Trial
- Polynucleotides High Purification Technology: A Real-World Prospective Study in a Hospital Outpatient Setting Supports PN HPT as a Regenerative Medicine Option for Acne Scar Management.Clinical, cosmetic and investigational dermatology · 2026Trial
- Development and Optimization of Retinyl Palmitate-Loaded Oleogel and Nanoemulsion Designed with Potential for Microneedling Treatment.Pharmaceuticals (Basel, Switzerland) · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionAcne vulgaris, affecting around 9.4% of the global population, is a common disorder of the pilosebaceous unit. Approximately 95% of affected individuals develop some degree of scarring, which, along with active acne, contributes significantly to psychosocial morbidity.
objectivesThis study aimed to evaluate the factors influencing acne severity, the development of acne scars, and the severity of scarring in patients with acne vulgaris.
methodsA cross-sectional study was conducted between May and November 2024 at the dermatology outpatient clinic of Ordu University, Turkey. Demographic data, characteristics of acne lesions, treatment history, and various potential risk factors for acne and scarring were recorded. Acne severity and scar severity were evaluated using standardized grading systems.
resultsA total of 269 patients (175 females, 94 males) were included, with acne scars observed in 71.3%. Younger age, earlier, and adolescent-onset acne were significantly associated with greater acne severity and scarring. Male sex and severe acne further increased the risk and severity of scars. Patients with scarring reported higher emotional stress. Post-lesional hyperpigmentation and erythema predicted more severe scarring. Prior use of topical agents and systemic antibiotics was linked to increased scar risk, while systemic isotretinoin had a protective effect.
conclusionsEarly identification of risk factors and timely intervention may help reduce the burden of acne scarring and improve patients' quality of life. Recognizing predictors of acne severity and scarring can guide clinicians in implementing preventive strategies and optimizing long-term outcomes.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.