ArticleDermatology practical & conceptual2025
Treatment Failure in Scabies: Assessment of Risk Factors in a Multicenter Cross-Sectional Study.
Article in Dermatology practical & conceptual, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- The Impact of Steroid Use on Scabies Treatment: An Evaluation of Clinical Severity, Parasite Burden, and the Validity of a Novel Scoring System.International journal of dermatology · 2026Article
- Scabies Treatment Failure: Beyond Drug Resistance and Toward a Multidimensional Understanding.Journal of tropical medicine · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionRecent reports of increased prevalence and treatment failure in scabies have raised concerns worldwide. Drug efficacy as well as adherence to treatment are important in treatment failure, and data on the latter are limited.
objectiveWe aimed to determine the factors associated with treatment failure in scabies.
methodsThis prospective, multicenter observational study was conducted in three centers, enrolling 230 patients diagnosed with scabies. Treatment outcomes were assessed one month after treatment initiation. Patients completed a questionnaire evaluating factors potentially affecting treatment outcomes. Demographic and clinical characteristics and adherence to treatment recommendations were compared in two groups: successful treatment and treatment failure.
resultsThe study included 125 males and 105 females, with a mean age of 24.6 ±17.6 years. Treatment failure was found in 58 patients (25.2%). No demographic parameter or medication was associated with treatment failure. Three independent risk factors for treatment failure (multivariate regression analysis) were lack of application of topical medication to the whole body, (odds ration (OR): 14.33; 95% confidence interval (CI): 2.9-71.4), lack of reapplication after washing hands (OR: 3.5; 95% CI: 1.5-8.0), and not reading of the information form (OR: 13.7; 95% CI: 1.3-80.6).
conclusionTreatment failure in scabies is quite common. Incorrect or incomplete application of topical treatment and lack of hygiene measures are the main factors leading to treatment failure. Providing a written information sheet with step-by-step treatment recommendations may contribute to treatment success.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.