Evidence map›Paper›PMID 41236222›Full record

ReviewDermatology practical & conceptual2025

Clinical Efficacy and Safety of Intralesional Bevacizumab in Dermatology: Insights from a Systematic Review.

Fereshte Rastegarnasab, Najmeh Tavousi, Mahsa Pourmahdi-Boroujeni, Kimia Afshar, Shadi Behfar, Bahareh Abtahi-Naeini

Abstract readReview
In one paragraph

Review in Dermatology practical & conceptual, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Fereshte RastegarnasabHypertension Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.
Najmeh TavousiStudent Research Committee, Isfahan University of Medical Sciences, Isfahan, Iran.
Mahsa Pourmahdi-BoroujeniStudent Research Committee, Isfahan University of Medical Sciences, Isfahan, Iran.
Kimia AfsharStudent Research Committee, Isfahan University of Medical Sciences, Isfahan, Iran.
Shadi BehfarRafsanjan University of Medical Sciences, Rafsanjan, Iran.
Bahareh Abtahi-NaeiniPediatric Dermatology Division of Department of Pediatrics, Imam Hossein Children's Hospital, Isfahan University of Medical Sciences, Isfahan, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionBevacizumab is a humanized monoclonal antibody specifically targeting the vascular endothelial growth factor (VEGF). In addition to cancer and ophthalmology, bevacizumab has other off-label uses. Among these, the treatment of hereditary hemorrhagic telangiectasia and hemangioma can be mentioned.

objectivesAlthough there are reports of successful treatments by bevacizumab, there is no systematic review on the topical use of this medication in dermatology. Therefore, this study aimed to investigate this topic.

methodsA systematic search on topical bevacizumab was done with MeSh-based keywords on online databases of PubMed, Scopus, and Web of Science in December 2022. The records were evaluated, and the eligible articles were selected.

resultsWe reviewed related studies, and the disease name, treatment protocol (injection dosage and intervals), outcomes, and complications were summarized for conclusions.

conclusionsIn this study, we systematically reviewed related papers and summarized the use of bevacizumab in dermatology in four categories, including hereditary hemorrhagic telangiectasia, vascular malformation, vascular proliferation, and others (lichen planus, and basal cell carcinoma).

Identifiers

PMID41236222
PMCPMC12615135

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.