Evidence map›Paper›PMID 41235590›Full record

ArticleAngewandte Chemie (International ed. in English)2026

Genetic Encoding of Pentafluorophosphato-Phenylalanine Provides PF

Anna Magdalena Ambros, Haocheng Qianzhu, Markus Tiemann, Edan Habel, Katrin Denzinger, Hana Zupan, Matteo Accorsi, Bettina G Keller, Gerhard Wolber, Thomas Huber and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Genetic Encoding of Pentafluorophosphato-Phenylalanine Provides PFAngewandte Chemie (International ed. in English) · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Anna Magdalena Ambros *Department of Biology, Chemistry, Pharmacy, Institute of Pharmacy, Freie Universität Berlin, Königin-Luise-Str. 2+4, 14195, Berlin, Germany.
Haocheng Qianzhu *Research School of Chemistry, Australian National University, Australian Capital Territory, 2601, Australia.
Markus TiemannDepartment of Biology, Chemistry, Pharmacy, Institute of Pharmacy, Freie Universität Berlin, Königin-Luise-Str. 2+4, 14195, Berlin, Germany.
Edan HabelResearch School of Chemistry, Australian National University, Australian Capital Territory, 2601, Australia.
Katrin DenzingerDepartment of Biology, Chemistry, Pharmacy, Institute of Pharmacy, Freie Universität Berlin, Königin-Luise-Str. 2+4, 14195, Berlin, Germany.
Hana ZupanDepartment of Biology, Chemistry, Pharmacy, Institute of Chemistry, Freie Universität Berlin, Arnimallee 22, 14195, Berlin, Germany.
Matteo AccorsiDepartment of Biology, Chemistry, Pharmacy, Institute of Pharmacy, Freie Universität Berlin, Königin-Luise-Str. 2+4, 14195, Berlin, Germany.
Bettina G KellerDepartment of Biology, Chemistry, Pharmacy, Institute of Chemistry, Freie Universität Berlin, Arnimallee 22, 14195, Berlin, Germany.
Gerhard WolberDepartment of Biology, Chemistry, Pharmacy, Institute of Pharmacy, Freie Universität Berlin, Königin-Luise-Str. 2+4, 14195, Berlin, Germany.
Thomas HuberResearch School of Chemistry, Australian National University, Australian Capital Territory, 2601, Australia.
Jörg RademannDepartment of Biology, Chemistry, Pharmacy, Institute of Pharmacy, Freie Universität Berlin, Königin-Luise-Str. 2+4, 14195, Berlin, Germany.ORCID 0000-0001-6678-3165

Funding

Australian Research Council DP230100079Australian Research Council DP240100273Deutsche Forschungsgemeinschaft Project-ID 387284271 - SFB 1349Elsa-Neumann Graduate Fellowship
6 · The paper itself

Abstract

Protein phosphorylation is one of the most important posttranslational modifications altering the structure, stability, and activity of more than 13 000 human proteins. In this work, the phosphotyrosine mimetic pentafluorophosphato-difluoromethyl-phenylalanine (PF

Indexed as

PhenylalaninePhosphoproteinsBacterial ProteinsHumansProtein Tyrosine Phosphatase, Non-Receptor Type 1Protein Tyrosine Phosphatase, Non-Receptor Type 11UbiquitinBacterial ProteinsIgG Fc-binding protein, StreptococcusPhenylalaninePhosphoproteinsProtein Tyrosine Phosphatase, Non-Receptor Type 1Protein Tyrosine Phosphatase, Non-Receptor Type 11UbiquitinGenetic encodingNon‐canonical amino acidsPentafluorophosphatesPhosphotyrosine mimeticsProtein tyrosine phosphatases

Identifiers

PMID41235590
PMCPMC12759244

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.