Evidence map›Paper›PMID 41235533›Full record

ArticleNMR in biomedicine2025

Renal Metabolic Rate of Oxygen in Response to Hypoxia Challenges by Means of Quantitative MRI in Humans.

Nada Kamona, Mahdie Hosseini, Michael C Langham, Felix W Wehrli

Abstract read
In one paragraph

Article in NMR in biomedicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nada KamonaDepartment of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID https://orcid.org/0000-0002-4382-876X
Mahdie HosseiniDepartment of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID https://orcid.org/0000-0001-6979-3780
Michael C LanghamDepartment of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID https://orcid.org/0000-0002-8733-1317
Felix W WehrliDepartment of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID https://orcid.org/0000-0003-3430-1840

Funding

High Spatial and Temporal Resolution MRI Mapping of Oxygen Consumption in HumansP41EB029460 · NIBIB · UNIVERSITY OF PENNSYLVANIA · PI Ravinder Reddy · 2021 to 2026
$7.6M
Training in Structural, Physiologic and Functional MRIT32EB020087 · NIBIB · UNIVERSITY OF PENNSYLVANIA · PI JAMES C GEE, Chamith Sudesh Rajapakse · 2016 to 2026
$2.1M
MRI-Based Renal Oximetry in Early Diabetic Kidney DiseaseR21DK132556 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI WEHRLI, FELIX W · 2023 to 2024
$439k
NIBIB NIH HHS P41 EB029460NIBIB NIH HHS T32 EB020087NIDDK NIH HHS R21 DK132556NIH HHS P41 EB029460NIH HHS R21 DK132556NIH HHS T32 EB020087
6 · The paper itself

Abstract

In early kidney disease, tissue hypoxia occurs due to an imbalance between ATP supply and demand. Whole-organ renal metabolic rate of oxygen (rMRO

Indexed as

HypoxiaKidneyMagnetic Resonance ImagingOxygenAdultFemaleHumansMaleMiddle AgedOxygen SaturationYoung AdultOxygenblood flowgraded hypoxiakidneyMRIoxygenation

Identifiers

PMID41235533
PMCPMC12616586

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.