ArticleClinical case reports2025
Guided Bone Regeneration (GBR) for Reconstructing Alveolar Bone Defects Following Resective Treatment of Medication-Related Osteonecrosis of the Jaws (MRONJ) Lesions: A Case Series.
Article in Clinical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Uncovering jaw-specific radiographic differences in medication related osteonecrosis of the jaws (MRONJ): a case-control study.Clinical oral investigations · 2026Article
- Guided Bone Regeneration (GBR) for Reconstructing Alveolar Bone Defects Following Resective Treatment of Medication-Related Osteonecrosis of the Jaws (MRONJ) Lesions: A Case Series.Clinical case reports · 2025Article
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Authors and funding
5 authors.
Funding
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Abstract
This case series describes three patients with medication-related osteonecrosis of the jaw (MRONJ) treated by surgical resection combined with guided bone regeneration (GBR). All patients had a history of prolonged antiresorptive therapy and developed stage 3 MRONJ following dentoalveolar procedures. Treatment consisted of marginal resection or sequestrectomy followed by GBR using combinations of different bone substitutes, membranes, and recombinant human bone morphogenetic protein-2 (rhBMP-2). Favorable healing was observed in all cases, with progressive bone regeneration confirmed radiographically and restoration of oral function achieved in two patients through successful implant rehabilitation. These findings suggest that MRONJ resection combined with GBR offers an effective, less invasive alternative to extensive reconstructive procedures in selected MRONJ patients, supporting both functional and esthetic rehabilitation while minimizing morbidity.
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