ArticleFrontiers in nutrition2025
Association of childhood-to-adolescence body mass index trajectories with elevated blood pressure and elevated carotid intima-media thickness.
Article in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Limited evidence exists on how early-life weight changes relate to cardiovascular damage in adolescents. We aimed to investigate the association between body mass index (BMI) trajectories from childhood to adolescence and elevated blood pressure (BP) and elevated carotid intima-media thickness (cIMT) in adolescents. Methods: This study included a total of 1,405 participants from the Huantai Children's Cardiovascular Health Cohort who had at least two BMI measurements between 2017 and 2023. Group-based trajectory modeling was used to identify distinct BMI trajectories. Logistic regression models were used to analyze the association between these BMI trajectories and the development of elevated BP and elevated cIMT. Results: The BMI trajectory patterns of participants from childhood to adolescence were categorized into three groups: low-and-increasing ( Conclusion: Consistently elevated BMI from childhood to adolescence is closely associated with elevated BP and elevated cIMT during adolescence. Obesity prevention and screening in youth should be prioritized to reduce future cardiovascular disease risk.
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