Evidence map›Paper›PMID 41235225›Full record

ArticleFrontiers in immunology2025

Uncovering the molecular and immunological defects in multicentric carpotarsal osteolysis syndrome: identification of relevant biomarkers.

Dorra Najjar, Asma Chikhaoui, Rim Boussetta, Saifeddine Azouz, Sinda Zarrouk, Sami Bouchoucha, Houda Yacoub-Youssef

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Article in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Dorra NajjarLaboratory of Biomedical Genomics and Oncogenetics, LR16IPT05, Institut Pasteur de Tunis, Tunis El Manar University, Tunis, Tunisia.
Asma ChikhaouiLaboratory of Biomedical Genomics and Oncogenetics, LR16IPT05, Institut Pasteur de Tunis, Tunis El Manar University, Tunis, Tunisia.
Rim BoussettaLaboratory of Biomedical Genomics and Oncogenetics, LR16IPT05, Institut Pasteur de Tunis, Tunis El Manar University, Tunis, Tunisia.
Saifeddine AzouzGenomics Platform, Institut Pasteur de Tunis, Tunis El Manar University, Tunis, Tunisia.
Sinda ZarroukGenomics Platform, Institut Pasteur de Tunis, Tunis El Manar University, Tunis, Tunisia.
Sami BouchouchaDepartment of Pediatric Orthopedic Surgery, Bechir Hamza Children's Hospital, Faculty of Medicine of Tunis, Tunis El Manar University, Tunis, Tunisia.
Houda Yacoub-YoussefLaboratory of Biomedical Genomics and Oncogenetics, LR16IPT05, Institut Pasteur de Tunis, Tunis El Manar University, Tunis, Tunisia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multicentric carpotarsal osteolysis (MCTO) is a rare genetic disease characterized by progressive osteolysis, often followed by nephropathy in advanced stages. It's caused by variants in the

Indexed as

MafB Transcription FactorOsteolysisAdolescentBiomarkersChildChild, PreschoolCytokinesFemaleHumansMaleMutationBiomarkersCytokinesMAFB protein, humanMafB Transcription Factorbone osteolysisinflammationjuvenile idiopathic arthritisMAFB genemulticentric carpotarsal osteolysisnephropathynon-steroid treatment

Identifiers

PMID41235225
PMCPMC12605331

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.