Parkinson Disease

Saud Alhusaini, Gabriel Dayanim, Mohamed Kandil, Lynne Krohn, Janine Molino, Ziv Gan-Or, Alain Dagher

Abstract read

In one paragraph

Article in Neurology. Genetics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Saud AlhusainiNeurology Department, Alpert Medical School of Brown University, Providence, RI.ORCID https://orcid.org/0000-0002-6869-3830

Gabriel DayanimNeurology Department, Alpert Medical School of Brown University, Providence, RI.ORCID https://orcid.org/0009-0009-3593-1132

Mohamed KandilNeurology Department, University of Alabama at Birmingham, AL.ORCID https://orcid.org/0009-0005-3593-2136

Lynne KrohnDepartment of Human Genetics, McGill University, Montreal, Quebec, Canada; and.ORCID https://orcid.org/0000-0001-6554-1666

Janine MolinoNeurology Department, Alpert Medical School of Brown University, Providence, RI.ORCID https://orcid.org/0000-0002-6258-3913

Ziv Gan-OrDepartment of Human Genetics, McGill University, Montreal, Quebec, Canada; and.ORCID https://orcid.org/0000-0003-0332-234X

Alain DagherDepartment of Neurology and Neurosurgery, McGill University, Montreal, Quebec, Canada.ORCID https://orcid.org/0000-0002-0945-5779

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: The aim of this study was to investigate the endophenotypic potential of striatal dopamine transporter (DAT) uptake in carriers of Parkinson disease (PD)-associated Methods: We analyzed 381 patients with de novo PD from the Parkinson's Progression Markers Initiative (PPMI). The genotype of previously identified PD-related Results: No significant associations were observed between Discussion: Our findings suggest that a more lateralized putaminal dopaminergic degeneration in early PD may represent a viable endophenotype in carriers of

Identifiers

PMID41235134

DOI10.1212/NXG.0000000000200327

PMCPMC12608047

What OpenQuestion holds

Textmetadata

LicenceCC BY-NC-ND

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.