Evidence map›Paper›PMID 41235052›Full record

ArticleJournal of preventive medicine and hygiene2025

Investigating the Theoretical Possibility of Dengue Fever in Ancient Egypt.

Francesco Maria Galassi, Michael Eduard Habicht, Mariano Martini, Mauro Vaccarezza, Donatella Lippi, Giorgia Cafici, Francesco Baldanzi, Elena Varotto

Abstract readHistorical Article
In one paragraph

Article in Journal of preventive medicine and hygiene, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Francesco Maria GalassiDepartment of Anthropology, Faculty of Biology and Environmental Protection, University of Lodz, Łódź, Poland.
Michael Eduard HabichtArchaeology, College of Humanities, Arts and Social Sciences, Flinders University, Adelaide, SA, Australia.
Mariano MartiniDepartment of Health Sciences, University of Genoa, Genoa, Italy.
Mauro VaccarezzaCurtin Medical School & Curtin Medical Research Institute (Curtin-MRI), Curtin University, Perth, Australia.
Donatella LippiDepartment of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
Giorgia CaficiDepartment of Cultures and Civilizations, University of Verona, Verona, Italy.
Francesco BaldanziDepartment of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
Elena VarottoArchaeology, College of Humanities, Arts and Social Sciences, Flinders University, Adelaide, SA, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dengue fever, a mosquito-borne viral disease primarily transmitted by Aedes aegypti, has become a growing global health concern, with dramatic increases in incidence in recent years. Although no direct evidence of dengue exists from ancient Egypt, this study investigates the theoretical possibility of its presence in that historical context. The approach integrates palaeoclimatic data, modern entomological and vector ecology studies, molecular clock analyses, and the interpretation of ancient Egyptian medical papyri. Special attention is given to the term temyt, described in association with dermatological and neurological symptoms in children and linked to the demon nesyt, as reinterpreted by scholars such as Bruno Halioua and Pascal Hannequin. These sources are critically re-evaluated alongside modern clinical symptomatology of dengue. Findings suggest that environmental and climatic conditions in ancient Egypt - particularly in regions like the Fayum- could have supported Aedes populations, and that certain disease descriptions may reflect empirical observations of vector-borne illnesses. While the evidence remains circumstantial and speculative, it opens new interpretative avenues regarding ancient Egyptian understandings of febrile, eruptive childhood diseases. The study concludes that dengue or dengue-like syndromes cannot be ruled out and that future interdisciplinary research, including palaeogenetic and archaeoviral approaches, may help clarify the presence of arboviral diseases in antiquity.

Indexed as

DengueAedesAnimalsEgyptEgypt, AncientHistory, AncientHumansMosquito VectorsAncient EgyptDenguefeverHistory of medicineInfectious diseasesMosquitoPalaeopathology

Identifiers

PMID41235052
PMCPMC12606527

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.