Evidence map›Paper›PMID 41235023›Full record

ArticleJBMR plus2025

Bone microarchitecture assessed by High-resolution peripheral quantitative computed tomography in type 1 diabetes: the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications study.

Mishaela Rubin, Galateia Kazakia, Barbara H Braffett, Naina Sinha Gregory, Ming-Hui Lin, Victoria Trapani, Ian H de Boer, Sanchita Agarwal, Andrew Burghardt, X Edward Guo and 3 more

Abstract read
In one paragraph

Article in JBMR plus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Mishaela RubinDivision of Endocrinology, Columbia University Irving Medical Center, New York, NY 10032, USA.
Galateia KazakiaDepartment of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA 94143, USA.ORCID https://orcid.org/0000-0002-7327-6425
Barbara H BraffettThe Biostatistics Center, George Washington University, Bethesda, MD 20817, USA.ORCID https://orcid.org/0000-0002-2184-9754
Naina Sinha GregoryDivision of Endocrinology, Diabetes, and Metabolism, Weill Cornell Medicine, New York, NY 10021, USA.
Ming-Hui LinThe Biostatistics Center, George Washington University, Bethesda, MD 20817, USA.
Victoria TrapaniThe Biostatistics Center, George Washington University, Bethesda, MD 20817, USA.
Ian H de BoerDivision of Nephrology, University of Washington, Seattle, WA 98195, USA.
Sanchita AgarwalDivision of Endocrinology, Columbia University Irving Medical Center, New York, NY 10032, USA.ORCID https://orcid.org/0000-0003-4978-0717
Andrew BurghardtDepartment of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA 94143, USA.ORCID https://orcid.org/0000-0002-6343-4944
X Edward GuoBone Bioengineering Laboratory, Department of Biomedical Engineering, Columbia University, New York, NY 10027, USA.ORCID https://orcid.org/0000-0003-0804-7279
Rose Gubitosi-KlugRainbow Babies and Children's Hospital, Case Western Reserve University, Cleveland, OH 44106, USA.
Ann V SchwartzDepartment of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA 94158, USA.ORCID https://orcid.org/0000-0003-4529-1641
DCCT/EDIC Research Group

Funding

Limited Competition for the Continuation of Epidemiology of Diabetes Interventions and Complications (EDIC) Study Clinical Research Center (Collaborative U01)U01DK094157 · NIDDK · CASE WESTERN RESERVE UNIVERSITY · PI Ionut Bebu, Barbara Halina Braffett · 2011 to 2026
$97.6M
Epidemiology of Diabetes Interventions and Complications Data Coordinating CenterU01DK094176 · NIDDK · GEORGE WASHINGTON UNIVERSITY · PI BEBU, IONUT, BRAFFETT, BARBARA HALINA · 2012 to 2022
$30.8M
Skeletal Biology and Biomechanics (SBB) CoreP30AR075055 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Wenhan Chang · 2019 to 2026
$7.1M
Effects of Biomedical Risk Factors on Neuro-cognition Using MRI: Long term follow-up of the Diabetes Control & Complications Trial/Epidemiology of Diabetes Interventions and Complications Study CohortDP3DK114812 · NIDDK · NYU WINTHROP HOSPITAL · PI JACOBSON, ALAN M · 2017 to 2019
$4.7M
NIAMS NIH HHS P30 AR075055NIDDK NIH HHS DP3 DK114812NIDDK NIH HHS U01 DK094157NIDDK NIH HHS U01 DK094176
6 · The paper itself

Abstract

The mechanism for bone fragility in type 1 diabetes (T1D) is unclear. We performed advanced analyses on HR-pQCT images from participants with T1D (

Indexed as

agingbone QCTbone quantificationdiabetesepidemiology

Identifiers

PMID41235023
PMCPMC12607258

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.